一例成人医源性右美托咪定意外过量的病例报告。
A case report of an accidental iatrogenic dexmedetomidine overdose in an adult.
作者信息
Tiainen Suvi-Maria, Unga Jonni, Uusalo Panu
机构信息
Department of Anaesthesiology and Intensive Care, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 51, Turku, FI-20521, Finland.
Division of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Kiinamyllynkatu 4-8, P.O. Box 51, Turku, FI-20521, Finland.
出版信息
Int J Emerg Med. 2024 Feb 27;17(1):27. doi: 10.1186/s12245-024-00613-5.
Abstract
BACKGROUND
Dexmedetomidine is a sedative drug with a wide safety margin.
CASE PRESENTATION
We present a case of accidental iatrogenic dexmedetomidine overdose in an adult patient during high-intensity focused ultrasound (HIFU) treatment. This is the first case report of an adult patient receiving an intravenous push of dexmedetomidine. Overdose resulted in severe oversedation, but symptoms receded spontaneously over time.
CONCLUSIONS
Dexmedetomidine overdoses are infrequent, and they are usually the result of an administration error.
摘要
背景
右美托咪定是一种安全范围广的镇静药物。
病例报告
我们报告一例成年患者在高强度聚焦超声（HIFU）治疗期间意外发生医源性右美托咪定过量的病例。这是首例成年患者静脉推注右美托咪定的病例报告。过量导致严重的过度镇静，但症状随时间自行消退。
结论
右美托咪定过量情况不常见，通常是给药错误所致。
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