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基于监督分块区域分割算法和特征组合迁移深度学习模型的乳腺超声图像自动识别。

Automatic Identification of Breast Ultrasound Image Based on Supervised Block-Based Region Segmentation Algorithm and Features Combination Migration Deep Learning Model.

出版信息

IEEE J Biomed Health Inform. 2020 Apr;24(4):984-993. doi: 10.1109/JBHI.2019.2960821. Epub 2019 Dec 19.

Abstract

Breast cancer is a high-incidence type of cancer for women. Early diagnosis plays a crucial role in the successful treatment of the disease and the effective reduction of deaths. In this paper, deep learning technology combined with ultrasound imaging diagnosis was used to identify and determine whether the tumors were benign or malignant. First, the tumor regions were segmented from the breast ultrasound (BUS) images using the supervised block-based region segmentation algorithm. Then, a VGG-19 network pretrained on the ImageNet dataset was applied to the segmented BUS images to predict whether the breast tumor was benign or malignant. The benchmark data for bio-validation were obtained from 141 patients with 199 breast tumors, including 69 cases of malignancy and 130 cases of benign tumors. The experiment showed that the accuracy of the supervised block-based region segmentation algorithm was almost the same as that of manual segmentation; therefore, it can replace manual work. The diagnostic effect of the combination feature model established based on the depth feature of the B-mode ultrasonic imaging and strain elastography was better than that of the model established based on these two images alone. The correct recognition rate was 92.95%, and the AUC was 0.98 for the combination feature model.

摘要

乳腺癌是女性高发的癌症类型。早期诊断对成功治疗疾病和有效降低死亡率至关重要。本文将深度学习技术与超声成像诊断相结合,用于识别和确定肿瘤是良性还是恶性。首先,使用基于监督的分块区域分割算法从乳腺超声(BUS)图像中分割出肿瘤区域。然后,将在 ImageNet 数据集上预训练的 VGG-19 网络应用于分割后的 BUS 图像,以预测乳腺肿瘤是良性还是恶性。生物验证的基准数据来自 141 名 199 个乳腺肿瘤患者,包括 69 例恶性肿瘤和 130 例良性肿瘤。实验表明,基于监督的分块区域分割算法的准确性几乎与手动分割相同;因此,它可以代替人工工作。基于 B 型超声成像和应变弹性成像深度特征建立的组合特征模型的诊断效果优于仅基于这两种图像建立的模型。组合特征模型的正确识别率为 92.95%,AUC 为 0.98。

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