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[头颈部腺样囊性癌的临床特征、治疗策略及预后]

[The clinical characteristic treatment strategy and prognosis of adenoid cystic carcinoma of the head and neck].

作者信息

Li Y, Deng W Y, Li N, Niu M K, Luo S X

机构信息

Department of gastroenterology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450000, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2019 Dec 23;41(12):932-936. doi: 10.3760/cma.j.issn.0253-3766.2019.12.009.

Abstract

To explore the clinical characteristics, treatment strategy and prognosis of adenoid cystic carcinoma of the head and neck (ACCHN). A retrospective analysis of the clinical and follow-up treatment of 79 patients with ACCHN from June 2008 to July 2017 was conducted in the Cancer Hospital of Zhengzhou University. A total of 79 ACCHN cases, including 31 males and 48 females. The age ranged from 19 to 77 (median, 52). The clinical manifestations of ACC were related to the locations of primary tumor.The mean size of the tumor was 2.6 cm (range from 1.5 to 7.7 cm). 50 of 79 patients with a definitive pathological diagnosis received surgical resection. 59 cases received chemotherapy and 62 cases received radiotherapy. With a median follow-up of 55 months, the 5-year, 10-year survival rate of these patients were 69.6% and 54.4%, respectively. ACCHN is an uncommon neoplasm with the characteristics of epithelial nerve growth, being inclined to distant metastasis, and high early misdiagnosis rate. The clinical manifestation, imaging and pathological result are need to be combined together to diagnose ACCHN.

摘要

探讨头颈部腺样囊性癌(ACCHN)的临床特征、治疗策略及预后。对郑州大学附属肿瘤医院2008年6月至2017年7月收治的79例ACCHN患者的临床资料及随访治疗情况进行回顾性分析。共79例ACCHN患者,其中男性31例,女性48例。年龄范围为19至77岁(中位年龄52岁)。ACCHN的临床表现与原发肿瘤部位有关。肿瘤平均大小为2.6 cm(范围为1.5至7.7 cm)。79例确诊病理诊断的患者中,50例行手术切除。59例接受化疗,62例接受放疗。中位随访55个月,这些患者的5年、10年生存率分别为69.6%和54.4%。ACCHN是一种少见肿瘤,具有上皮神经生长、易远处转移及早期误诊率高的特点。ACCHN的诊断需结合临床表现、影像学及病理结果。

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