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甲状腺疾病患者的医疗连续性与2型糖尿病发生之间的关联。

Association between continuity of care and type 2 diabetes development among patients with thyroid disorder.

作者信息

Lee Sang Ah, Choi Dong-Woo, Kwon Junhyun, Lee Doo Woong, Park Eun-Cheol

机构信息

Department of Public Health, Graduate School.

Institute of Health Services Research, Yonsei University, Seoul.

出版信息

Medicine (Baltimore). 2019 Dec;98(52):e18537. doi: 10.1097/MD.0000000000018537.

Abstract

Thyroid disorders are associated with blood glucose abnormalities. For rendering the patients euthyroid, routine screening and care are essential. Therefore, the aim of this study was to investigate the association between continuity of care (COC) and type 2 diabetes onset among patients with thyroid disorders.We used the national claim data. Our study population was 4099 patients with hyperthyroidism or hypothyroidism. For calculating COC, the Most Frequent Provider Continuity Index (MFPCI), Modified Modified Continuity Index (MMCI), and COC Index (COCI) were used. The dependent variable was type 2 diabetes onset. The Cox proportional hazard regression model was used.Among 4099 patients with thyroid disorders, 25.3% experienced onset of type 2 diabetes. Thyroid patients who had MFPCI and COCI below the median were more likely to experience onset of type 2 diabetes than who had these indices above the median (MFPCI: hazard ratio [HR] = 1.26, 95% confidence interval [CI] = 1.09-1.46; COCI: HR = 1.22, 95% CI = 1.06-1.41). Our subgroup analysis showed that female patients and those 20 to 34 years of age showed a significant association between COC and onset of type 2 diabetes.Patients with thyroid disorders with low COC showed an increased risk of developing type 2 diabetes. Therefore, efforts to enhance COC among patients with thyroid disorders needs to be encouraged.

摘要

甲状腺疾病与血糖异常有关。为使患者甲状腺功能正常,常规筛查和护理至关重要。因此,本研究的目的是调查甲状腺疾病患者的连续护理(COC)与2型糖尿病发病之间的关联。我们使用了国家索赔数据。我们的研究人群为4099例甲亢或甲减患者。为计算COC,使用了最频繁提供者连续性指数(MFPCI)、改良连续性指数(MMCI)和COC指数(COCI)。因变量为2型糖尿病发病。使用了Cox比例风险回归模型。在4099例甲状腺疾病患者中,25.3%发生了2型糖尿病。MFPCI和COCI低于中位数的甲状腺疾病患者比这些指数高于中位数的患者更有可能发生2型糖尿病(MFPCI:风险比[HR]=1.26,95%置信区间[CI]=1.09-1.46;COCI:HR=1.22,95%CI=1.06-1.41)。我们的亚组分析表明,女性患者以及年龄在20至34岁之间的患者,COC与2型糖尿病发病之间存在显著关联。COC较低的甲状腺疾病患者患2型糖尿病的风险增加。因此,需要鼓励努力提高甲状腺疾病患者的COC。

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