Martín García E, Chávarri García J J, Rodríguez Vicente L, Jiménez Del Río B, Guallar Leza S M, Del Río Mayor J L
Servicio de Oftalmología, Hospital San Pedro, Logroño, La Rioja, España.
Servicio de Oftalmología, Hospital San Pedro, Logroño, La Rioja, España.
Arch Soc Esp Oftalmol (Engl Ed). 2020 Feb;95(2):90-93. doi: 10.1016/j.oftal.2019.11.003. Epub 2019 Dec 23.
A 12-year-old patient diagnosed with congenital toxoplasmosis, with no systemic treatment at the time, who presented with a decreased visual acuity (VA) in his left eye (LE). On examination, VA in the LE was 0.05 and the fundus examination revealed a focus of chorioretinitis adjacent to a pigmented macular scar, as well as a large associated subretinal haemorrhage. After confirming the diagnosis of choroidal neovascular membrane secondary to ocular toxoplasmosis, treatment was started with systemic anti-toxoplasmosis drugs and two anti-VEGF intravitreal injections separated by one month. Finally, the patients had a VA in LE of 0.4, with reabsorption of the haemorrhage, leaving an inactive pigmented macular scar. The use of anti-VEGF intravitreal injections in cases of ocular toxoplasmosis has been associated with a reactivation of old lesions, so the prophylactic use of oral anti-toxoplasmosis drugs is recommended in these cases.
一名12岁患者被诊断为先天性弓形虫病，当时未接受全身治疗，左眼视力下降。检查发现，左眼视力为0.05，眼底检查显示脉络膜视网膜炎病灶邻近色素性黄斑瘢痕，以及大片相关的视网膜下出血。在确诊为眼部弓形虫病继发脉络膜新生血管膜后，开始使用全身抗弓形虫药物治疗，并在一个月内进行了两次玻璃体内抗VEGF注射。最后，患者左眼视力为0.4，出血吸收，留下无活性的色素性黄斑瘢痕。在眼部弓形虫病病例中使用玻璃体内抗VEGF注射与旧病灶重新激活有关，因此在这些病例中建议预防性使用口服抗弓形虫药物。
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