Novikova R I, Cherniĭ V I, Gorodnik G A, Mareeva T E
Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(6):85-8.
In an intensive care unit, 181 patients were electrophysiologically investigated (impedance measuring, rheoencephalography, echoencephalography) and ophthalmoscopied, their plasma and red blood cells electrolytes, red blood cells ATP, levels of histamine, serotonin, and monoamine oxidase activity measured and the state of the lipid peroxidation system determined. The combined investigation ensured the early detection of brain edema or swelling and assessment of preponderance of either process. Increase in serotonin, histamine levels and activation of lipid peroxidation system were shown to play an important role in the pathogenesis of these disorders.
在重症监护病房，对181例患者进行了电生理检查（阻抗测量、脑血流图、脑回波图）和检眼镜检查，测量了他们的血浆和红细胞电解质、红细胞三磷酸腺苷、组胺、血清素水平以及单胺氧化酶活性，并测定了脂质过氧化系统的状态。综合检查确保了早期发现脑水肿或肿胀，并评估了任一过程的优势。血清素、组胺水平的升高以及脂质过氧化系统的激活在这些疾病的发病机制中起着重要作用。
