Zozulia Iu A, Chepkiĭ L P, Gavrish R V, Iarotskiĭ R Iu
Zh Vopr Neirokhir Im N N Burdenko. 1997 Jul-Sep(3):18-22.
A hundred and sixteen postoperative patients after removal of various brain tumors in whom brain edema developed were treated with 1-3 courses of blood ultrafiltration (BUF). 0.5-9.0 liters of ultrafiltrate was removed. BUF does not lead to blood concentration due to the movement of the fluid from intracellular to intravascular space. BUF allows to decrease the amount of toxic medium-sized peptides and osmolarity discriminant. Seldom the minor complications were observed because of usage of the plate shaped dialyzers. When the capillary dialyzers were used, no complications were noted. BUF may be recommended in patients with brain tumors in early postoperative period when traditional medical management does not seem to be effective enough. The technique helps to reduce the duration of brain edema in treated patients by 8-10 days vs. controls treated traditionally.
116例各种脑肿瘤切除术后发生脑水肿的患者接受了1 - 3个疗程的血液超滤（BUF）治疗。共去除0.5 - 9.0升超滤液。由于液体从细胞内转移到血管内空间，BUF不会导致血液浓缩。BUF可以减少有毒的中等大小肽的数量和渗透压差异。由于使用平板型透析器，很少观察到轻微并发症。使用毛细管透析器时，未发现并发症。当传统药物治疗似乎不够有效时，BUF可推荐用于术后早期的脑肿瘤患者。与传统治疗的对照组相比，该技术有助于将治疗患者的脑水肿持续时间缩短8 - 10天。
