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基于台湾全民健康保险牙科数据集的确诊涎石病患病率的时间趋势。

Time trends in the prevalence of diagnosed sialolithiasis from Taiwanese nationwide health insurance dental dataset.

作者信息

Wang Yu-Hsun, Chen Yi-Tzu, Chiu Yu-Wei, Yu Hui-Chieh, Chang Yu-Chao

机构信息

Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.

Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan.

出版信息

J Dent Sci. 2019 Dec;14(4):365-369. doi: 10.1016/j.jds.2019.04.003. Epub 2019 May 28.

Abstract

BACKGROUND/PURPOSE: Sialolithiasis, the so-called salivary gland stone, is a condition forming salivary calculi within a salivary gland or ducts. Little is known about the epidemiological survey of sialolithiasis in Taiwanese population. In this study, we conducted an age-period-cohort (APC) analysis evaluating the prevalence of sialolithiasis.

MATERIALS AND METHODS

A retrospective study was conducted to analyze the registered database compiled by the Taiwanese National Health Insurance Research Database from 1996 to 2013. The APC analysis was performed to investigate the effects of age, diagnosis period, and birth cohort with sialolithiasis.

RESULTS

We found that the prevalence of sialolithiasis varied from 1.4 (10) to 2.3 (10). The mean age ±standard deviation with sialolithiasis from 1996 to 2013 was 37.7 ± 18.5 and 46.2 ± 18.6 years old, respectively. The prevalence was higher among male than female (RR: 1.10; 95% CI: 1.05-1.15, p < 0.001). The age >65 group had higher risk compared to age <40 group (RR: 2.27; 95% CI: 2.13-2.43, p < 0.001). The relative risk for sialolithiasis demonstrated significant age effect (p < 0.001). The relative risk for sialolithiasis did not show the significant period effect (p = 0.742). The relative risk for sialolithiasis demonstrated significant cohort effect (p = 0.01). The relative risk for sialolithiasis demonstrated significant APC effect (p = 0.002).

CONCLUSION

Form this nationwide population-based database, the prevalence of sialolithiasis occurs more frequently in male than in female. In addition, the relative risk for sialolithiasis demonstrated the significant APC effects.

摘要

背景/目的:涎石病,即所谓的唾液腺结石,是一种在唾液腺或导管内形成唾液结石的病症。关于台湾人群涎石病的流行病学调查知之甚少。在本研究中,我们进行了年龄-时期-队列(APC)分析,以评估涎石病的患病率。

材料与方法

进行了一项回顾性研究,分析台湾国民健康保险研究数据库1996年至2013年汇编的注册数据库。进行APC分析以研究年龄、诊断时期和出生队列对涎石病的影响。

结果

我们发现涎石病的患病率在1.4(10)至2.3(10)之间变化。1996年至2013年患涎石病的平均年龄±标准差分别为37.7±18.5岁和46.2±18.6岁。男性患病率高于女性(RR:1.10;95%CI:1.05 - 1.15,p<0.001)。65岁以上组比40岁以下组风险更高(RR:2.27;95%CI:2.13 - 2.43,p<0.001)。涎石病的相对风险显示出显著的年龄效应(p<0.001)。涎石病的相对风险未显示出显著的时期效应(p = 0.742)。涎石病的相对风险显示出显著的队列效应(p = 0.01)。涎石病的相对风险显示出显著的APC效应(p = 0.002)。

结论

从这个基于全国人群的数据来看,涎石病在男性中的患病率高于女性。此外,涎石病的相对风险显示出显著的APC效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe1/6921131/2cb309d3d61b/gr1.jpg

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