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一项基于全台湾地区登记系统的关于2004年至2013年灼口综合征患病率的研究。

A nationwide register-based study of the prevalence of burning mouth syndrome in Taiwan from 2004 to 2013.

作者信息

Su Ni-Yu, Wang Yu-Hsun, Chang Yu-Chao

机构信息

School of Dentistry, Chung Shan Medical University, Taichung, Taiwan.

Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan.

出版信息

J Dent Sci. 2021 Oct;16(4):1074-1079. doi: 10.1016/j.jds.2021.06.020. Epub 2021 Jul 12.

Abstract

BACKGROUND/PURPOSE: Burning mouth syndrome (BMS) is defined as a chronic burning pain of the oral mucosa with no associated clinical signs or apparent extraneous cause. Limited epidemiologic data have been published. In this study, we probed the nationwide registered database to assess the prevalence of BMS in Taiwan.

MATERIALS AND METHODS

A retrospective study was conducted to analyze the dental dataset compiled by the Taiwan's National Health Insurance Research Database from 2004 to 2013. The diagnosis of BMS was identified in accordance with the International Classification of Disease, Ninth revision. In addition, sex and age were analyzed by multivariate Poisson regression.

RESULTS

The prevalence of BMS revealed from 2.24 (per 10) to 3.11 (per 10) over past 10 year period. Female has higher risk of BMS than male (RR: 1.39; 95% CI: 1.37-1.41). The 50-59 years old group, 60-69 years old group, and >70 years old group had 1.55-, 2.06-, and 2.58-fold risk than 40-49 years old group for BMS (p < 0.001), respectively.

CONCLUSION

Taken together, this is the first reported nationwide population based prevalence data for BMS in Taiwan. The risk for BMS is highly associated with female and advancing age.

摘要

背景/目的:灼口综合征(BMS)被定义为口腔黏膜的慢性灼痛,无相关临床体征或明显的外部病因。已发表的流行病学数据有限。在本研究中,我们调查了全国注册数据库以评估台湾地区BMS的患病率。

材料与方法

进行一项回顾性研究,分析台湾国民健康保险研究数据库在2004年至2013年期间汇编的牙科数据集。BMS的诊断依据国际疾病分类第九版确定。此外,通过多变量泊松回归分析性别和年龄。

结果

在过去10年期间,BMS的患病率为每10人中有2.24至3.11人。女性患BMS的风险高于男性(相对危险度:1.39;95%可信区间:1.37 - 1.41)。50 - 59岁组、60 - 69岁组和70岁以上组患BMS的风险分别是40 - 49岁组的1.55倍、2.06倍和2.58倍(p < 0.001)。

结论

总体而言,这是台湾地区首次报道的基于全国人口的BMS患病率数据。BMS的风险与女性和年龄增长高度相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f786/8403878/53a112ef178c/gr1.jpg

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