Miller R H, Horneffer P J, Gardner T J, Rykiel M F, Pearson T A
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Md.
Am Heart J. 1988 Nov;116(5 Pt 1):1323-9. doi: 10.1016/0002-8703(88)90457-7.
PPS is a major cause of morbidity after cardiac surgery and may cause bypass graft closure and fatal cardiac tamponade. Little is known about its incidence and cause. To better define this syndrome characterized by postoperative fever, pericardial friction rub, and pericardial pain, we used two out of three of the preceding criteria to diagnose PPS. In a prospective epidemiologic study we followed 944 consecutive patients undergoing open-heart surgery between November 1984 and November 1985. The overall incidence was 17.8%. The incidence was increased in younger patients, in those with a history of prednisone use in the past, in patients with a past history of pericarditis, those with aortic valve replacement, and in patients who received enflurane or halothane anesthesia. PPS is a common syndrome. Knowledge of risk factors associated with PPS may allow its prevention and identification of patients who warrant early and aggressive treatment.
心包切开术后综合征（PPS）是心脏手术后发病的主要原因，可能导致旁路移植血管闭塞和致命性心包填塞。对其发病率和病因了解甚少。为了更好地界定这种以术后发热、心包摩擦音和心包疼痛为特征的综合征，我们采用上述三项标准中的两项来诊断PPS。在一项前瞻性流行病学研究中，我们对1984年11月至1985年11月期间连续接受心脏直视手术的944例患者进行了随访。总体发病率为17.8%。年轻患者、既往有使用泼尼松病史的患者、既往有心包炎病史的患者、接受主动脉瓣置换术的患者以及接受恩氟烷或氟烷麻醉的患者发病率升高。PPS是一种常见综合征。了解与PPS相关的危险因素可能有助于预防该综合征，并识别需要早期积极治疗的患者。
