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急性憩室炎发作后结肠镜检查的疗效及结直肠癌风险

Efficacy of colonoscopy after an episode of acute diverticulitis and risk of colorectal cancer.

作者信息

Díaz Jeancarlos Jhosmer Trujillo, Asenjo Beatriz De Andrés, Soriano María Ruiz, Fernández Carlos Jezieniecki, Aurusa Javier Ortiz de Solórzano, Rentería Juan Pablo Beltrán de Heredia

机构信息

Department of General and Digestive Surgery, (Jeancarlos Jhosmer Trujillo Díaz, Beatriz De Andrés Asenjo, María Ruiz Soriano, Carlos Jezieniecki Fernández, Javier Ortiz de Solórzano Aurusa, Juan Pablo Beltrán de Heredia y Rentería).

Colorectal Surgery Unit (Jeancarlos Jhosmer Trujillo Díaz, Beatriz De Andrés Asenjo, Javier Ortiz de Solórzano Aurusa), Valladolid University Clinic Hospital, Spain.

出版信息

Ann Gastroenterol. 2020 Jan-Feb;33(1):68-72. doi: 10.20524/aog.2019.0437. Epub 2019 Nov 29.

Abstract

BACKGROUND

Diverticular disease of the colon has a high global prevalence. The guidelines suggest performing a colonoscopy 4-6 weeks after the acute episode to exclude colorectal cancer (CRC). However, these recommendations are based on old studies, when computed tomography was not used to diagnose acute diverticulitis (AD). There are currently some studies showing that CRC incidence is low in uncomplicated AD (UAD). Therefore, we decided to perform this study to determine the CRC incidence after an AD episode and the diagnostic efficacy of colonoscopy in these patients.

METHOD

This was a retrospective cohort study that included patients with AD between July 2016 and December 2017.

RESULTS

One hundred seventy-four patients had AD. Of these, 46 patients were excluded and we analyzed 128 patients, 72 (56.3%) women and 56 (43.7%) men. Ninety (70.3%) had UAD and 38 (29.7%) complicated AD (CAD). The colonoscopy showed lesions in 18 (14.06%), 5 (3.9%) being CRC. The patients with CRC had shown CAD and were >70 years old (P=0.0001 and P=0.002 respectively).

CONCLUSIONS

Routine colonoscopy in patients with UAD appears not have many benefits as a diagnostic tool. However, it has a higher efficacy if the patients have CAD and are >70 years old.

摘要

背景

结肠憩室病在全球具有较高的患病率。指南建议在急性发作后4 - 6周进行结肠镜检查以排除结直肠癌(CRC)。然而,这些建议是基于旧的研究,当时计算机断层扫描尚未用于诊断急性憩室炎(AD)。目前有一些研究表明,非复杂性AD(UAD)患者的CRC发病率较低。因此,我们决定开展这项研究,以确定AD发作后的CRC发病率以及结肠镜检查对这些患者的诊断效能。

方法

这是一项回顾性队列研究,纳入了2016年7月至2017年12月期间患有AD的患者。

结果

174例患者患有AD。其中,46例患者被排除,我们分析了128例患者,72例(56.3%)为女性,56例(43.7%)为男性。90例(70.3%)患有UAD,38例(29.7%)患有复杂性AD(CAD)。结肠镜检查发现18例(14.06%)有病变,其中5例(3.9%)为CRC。患有CRC的患者表现为CAD且年龄>70岁(分别为P = 0.0001和P = 0.002)。

结论

UAD患者进行常规结肠镜检查作为诊断工具似乎没有太多益处。然而,如果患者患有CAD且年龄>70岁,其诊断效能更高。

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