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单纯性憩室炎首次发作不会增加结直肠癌的风险。

First episode of uncomplicated diverticulitis does not increase the risk of colorectal cancer.

机构信息

Department of Surgery, Zealand University Hospital, Denmark.

出版信息

Dan Med J. 2022 Mar 11;69(4):A04210354.

Abstract

INTRODUCTION

Danish guidelines recommend colonoscopy after a case of acute diverticulitis to exclude colorectal cancer (CRC), but evidence in support this practice is limited. A series of studies has reported a low incidence of CRC in patients after they presented with acute diverticulitis, especially in uncomplicated cases. The purpose of this study was to investigate the incidence of CRC after acute diverticulitis detected during colonoscopy.

METHODS

All patients seen between January 2010 and November 2017 with a first episode of acute diverticulitis and a subsequent computed tomography and colonoscopy were included.

RESULTS

A total of 332 patients were included in the study. The incidence of CRC after a case of uncomplicated acute diverticulitis was 0.8%. The incidence of malignancy was 2.8% in the group of patients with complicated diverticulitis.

CONCLUSIONS

This study showed a low risk of CRC after a case of acute diverticulitis and no cases of CRC in patients with uncomplicated diverticulitis without clinical symptoms of CRC. This indicates that revising guidelines in regards to follow-up after diverticulitis may be warranted.

FUNDING

none.

TRIAL REGISTRATION

not relevant.

摘要

简介

丹麦指南建议在急性憩室炎病例后进行结肠镜检查以排除结直肠癌(CRC),但支持这种做法的证据有限。一系列研究报告称,在出现急性憩室炎的患者中,CRC 的发病率较低,尤其是在无并发症的情况下。本研究旨在调查结肠镜检查中发现的急性憩室炎后 CRC 的发生率。

方法

纳入 2010 年 1 月至 2017 年 11 月间首次出现急性憩室炎并随后进行计算机断层扫描和结肠镜检查的所有患者。

结果

共有 332 例患者纳入研究。单纯性急性憩室炎后 CRC 的发生率为 0.8%。复杂性憩室炎患者组中恶性肿瘤的发生率为 2.8%。

结论

本研究表明急性憩室炎后 CRC 的风险较低,且无临床症状的单纯性憩室炎患者无 CRC 病例。这表明可能需要修订关于憩室炎后随访的指南。

无资金来源。

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