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以心包积液为表现的乳腺转移性导管腺癌——乳腺癌诊断中的挑战

Metastatic ductal adenocarcinoma of the breast presenting with pericardial effusion-Challenges in the diagnosis of breast cancer.

作者信息

Chahin Michael, Seegobin Karan, Maharaj Satish, Ramsubeik Karishma

机构信息

Division of Internal Medicine Department of Medicine University of Florida College of Medicine Jacksonville FL USA.

Division of Rheumatology and Clinical Immunology Department of Medicine University of Florida College of Medicine Jacksonville FL USA.

出版信息

Clin Case Rep. 2019 Oct 24;7(12):2384-2387. doi: 10.1002/ccr3.2497. eCollection 2019 Dec.

DOI:10.1002/ccr3.2497
PMID:31893064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6935662/
Abstract

Breast cancer is a common entity that can be difficult to diagnose. This case demonstrates the limitations of breast cancer diagnostics. Particularly, how the available imaging techniques and even biopsy can potentially miss a malignancy. It exemplifies the role immunohistochemistry staining plays in the diagnosis of cancers of unclear origin.

摘要

乳腺癌是一种常见病症,可能难以诊断。本病例展示了乳腺癌诊断的局限性。特别是,现有的成像技术甚至活检都有可能漏诊恶性肿瘤。它例证了免疫组化染色在不明来源癌症诊断中所起的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/6f6f0b58dca7/CCR3-7-2384-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/593b19c2ca7a/CCR3-7-2384-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/e885ba71acd6/CCR3-7-2384-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/6f6f0b58dca7/CCR3-7-2384-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/593b19c2ca7a/CCR3-7-2384-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/e885ba71acd6/CCR3-7-2384-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2b/6935662/6f6f0b58dca7/CCR3-7-2384-g003.jpg

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本文引用的文献

1
Association of Digital Breast Tomosynthesis vs Digital Mammography With Cancer Detection and Recall Rates by Age and Breast Density.数字乳腺断层合成摄影术与数字乳腺 X 线摄影术对年龄和乳腺密度相关的癌症检出率和召回率的比较。
JAMA Oncol. 2019 May 1;5(5):635-642. doi: 10.1001/jamaoncol.2018.7078.
2
Occult breast cancer may originate from ectopic breast tissue present in axillary lymph nodes.隐匿性乳腺癌可能起源于腋窝淋巴结中存在的异位乳腺组织。
Breast Cancer Res Treat. 2018 Nov;172(1):1-7. doi: 10.1007/s10549-018-4898-4. Epub 2018 Jul 20.
3
Immunohistochemistry for Diagnosis of Metastatic Carcinomas of Unknown Primary Site.
免疫组织化学在原发部位不明转移性癌诊断中的应用
Cancers (Basel). 2018 Apr 5;10(4):108. doi: 10.3390/cancers10040108.
4
Contrast Enhanced Spectral Mammography: A Review.对比增强光谱乳腺摄影术:综述
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ACR Appropriateness Criteria Breast Cancer Screening.美国放射学会(ACR)乳腺癌筛查适宜性标准
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6
Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality.心包炎作为隐匿性癌症的标志物及癌症死亡率的预后因素
Circulation. 2017 Sep 12;136(11):996-1006. doi: 10.1161/CIRCULATIONAHA.116.024041. Epub 2017 Jun 29.
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Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial.钼靶 X 线摄影和附加超声检查筛查乳腺癌的敏感性和特异性:日本策略性抗癌随机试验(J-START):一项随机对照试验。
Lancet. 2016 Jan 23;387(10016):341-348. doi: 10.1016/S0140-6736(15)00774-6. Epub 2015 Nov 5.
8
Malignancies in systemic lupus erythematosus: a 2015 update.系统性红斑狼疮中的恶性肿瘤:2015年更新
Curr Opin Rheumatol. 2015 Sep;27(5):454-60. doi: 10.1097/BOR.0000000000000202.
9
Occult primary breast cancer at a comprehensive cancer center.综合性癌症中心的隐匿性原发性乳腺癌。
J Surg Res. 2013 Dec;185(2):684-9. doi: 10.1016/j.jss.2013.06.020. Epub 2013 Jul 2.
10
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Pol J Radiol. 2011 Jan;76(1):25-9.