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听诊胎儿心率加速。三、振动声学刺激的应用。

Auscultated fetal heart rate accelerations. III. Use of vibratory acoustic stimulation.

作者信息

Paine L L, Johnson T R, Alexander G R

机构信息

Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Am J Obstet Gynecol. 1988 Nov;159(5):1163-7. doi: 10.1016/0002-9378(88)90437-1.

Abstract

The auscultated acceleration test has been proposed as a simple, inexpensive screening test for fetal health; previous studies of the auscultated acceleration test used external stimulation to elicit fetal movement. This study was conducted to explore the ability of the auscultated acceleration test to predict nonstress test results when vibratory acoustic stimulation is used to elicit fetal reactivity. After antepartum nonstress testing on 100 gravid women between 28 and 43 weeks' gestation, a 6-minute auscultated acceleration test protocol was performed with two vibratory acoustic stimulations to the maternal abdomen if no spontaneous fetal heart rate acceleration occurred. The ability of the auscultated acceleration test to predict nonstress test results after selected variables were controlled for was as follows: sensitivity, 75%; specificity, 97.6%; false-positive results, 14.3%; and false-negative results, 4.7%. Logistic regression analysis indicated that, in addition to the auscultated acceleration test, gestational age and race contributed significantly to the prediction of nonstress test results. Although specificity and the false-positive rate were improved, the use of vibratory acoustic stimulations to elicit fetal movement did not improve the validity of the auscultated acceleration test in terms of sensitivity and false-negative results over previous studies. However, the auscultated acceleration test continues to show potential as an initial screening test for fetal assessment. In addition to recommendations for further research, methodologic issues related to sampling techniques are identified.

摘要

听诊加速试验已被提议作为一种简单、廉价的胎儿健康筛查试验;先前关于听诊加速试验的研究使用外部刺激来诱发胎儿运动。本研究旨在探讨当使用振动听觉刺激来诱发胎儿反应性时,听诊加速试验预测无应激试验结果的能力。在对100名妊娠28至43周的孕妇进行产前无应激试验后,如果未出现自发的胎儿心率加速,则对孕妇腹部进行两次振动听觉刺激,执行6分钟的听诊加速试验方案。在控制选定变量后,听诊加速试验预测无应激试验结果的能力如下:敏感性为75%;特异性为97.6%;假阳性结果为14.3%;假阴性结果为4.7%。逻辑回归分析表明,除了听诊加速试验外,胎龄和种族对无应激试验结果的预测也有显著贡献。尽管特异性和假阳性率有所提高,但与先前的研究相比,使用振动听觉刺激来诱发胎儿运动在敏感性和假阴性结果方面并未提高听诊加速试验的有效性。然而,听诊加速试验作为胎儿评估的初始筛查试验仍显示出潜力。除了对进一步研究的建议外,还确定了与采样技术相关的方法学问题。

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