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听诊加速试验中两个时间间隔的比较。

A comparison of two time intervals for the ausculated acceleration test.

作者信息

Paine L L, Zanardi L R, Johnson T R, Rorie J A, Barger M K

机构信息

Department of Maternal and Child Health at the Boston University School of Public Health, MA 02118-2526, USA.

出版信息

J Midwifery Womens Health. 2001 Mar-Apr;46(2):98-102. doi: 10.1016/s1526-9523(01)00102-7.

Abstract

OBJECTIVE

Interest in an inexpensive, easy-to-administer antenatal screening test that did not rely on the use of electronic fetal monitoring led to development of the fetoscope administered auscultated acceleration test (AAT) in the late 1980s. More recent efforts have been directed toward providing those who may use the AAT with important information about the most effective and clinically appropriate AAT procedures. The purpose of this study was to determine the screening test validity performance of two AAT time intervals--6 minutes and 10 minutes.

METHODS

Two auscultated acceleration tests (AAT6 and AAT10) were simultaneously performed using different time intervals on 205 women with high-risk pregnancies undergoing simultaneous nonstress tests (NSTS) who were referred to a tertiary care unit for antepartum testing. Standard measurements of screening test validity were calculated for each test in the prediction of selected perinatal outcomes. NST findings were included for comparative purposes.

RESULTS

The AAT6 yielded an overall higher specificity as compared with the AAT10 at the expense of a slightly lower sensitivity for most perinatal outcomes; these differences were not significant at the .05 level. Relative risk ratios were similar for the AAT6 and AAT10 for both fetal distress and neonatal morbidity, with both AAT being a more effective predictor of neonatal morbidity than for fetal distress. Both tests yielded better sensitivity when compared with NST.

CONCLUSIONS

Even though there was a nonsignificant trend toward higher sensitivities and lower specificities for the 10-minute AAT, this study showed that the differences in prediction of perinatal outcomes between the 6-minute and 10-minute AAT were minimal. In view of the added labor required for the 10-minute AAT in the absence of enhanced screening test validity, the 6-minute AAT is clinically preferred. This study has prompted new research questions for the continued development of the AAT as a low-technology fetal assessment technique with potential usefulness by midwives and their colleagues in a variety of settings worldwide.

摘要

目的

由于对一种价格低廉、易于实施且不依赖电子胎儿监护的产前筛查试验感兴趣,催生了20世纪80年代末的胎儿镜听诊加速试验(AAT)。最近的努力旨在为可能使用AAT的人员提供有关最有效且临床适用的AAT程序的重要信息。本研究的目的是确定两个AAT时间间隔(6分钟和10分钟)的筛查试验有效性表现。

方法

对205名高危妊娠且同时进行无应激试验(NST)的孕妇在三级医疗机构接受产前检查时,使用不同时间间隔同时进行两次听诊加速试验(AAT6和AAT10)。计算每次试验在预测选定围产期结局时筛查试验有效性的标准测量值。纳入NST结果用于比较。

结果

与AAT10相比,AAT6总体特异性更高,但对大多数围产期结局的敏感性略低;在0.05水平上,这些差异不显著。AAT6和AAT10在胎儿窘迫和新生儿发病率方面的相对风险比相似,两种AAT对新生儿发病率的预测比胎儿窘迫更有效。与NST相比,两种试验的敏感性均更高。

结论

尽管10分钟AAT有敏感性更高、特异性更低的不显著趋势,但本研究表明,6分钟和10分钟AAT在围产期结局预测方面的差异极小。鉴于10分钟AAT在未提高筛查试验有效性的情况下增加了工作量,临床上更倾向于6分钟AAT。本研究引发了新的研究问题,以继续开发AAT作为一种低技术胎儿评估技术,供全球各地各种环境中的助产士及其同事使用,具有潜在用途。

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