Institute of Andrology, Department of Urology, University College London Hospitals NHS Trust.
NIHR Biomedical Research Centre, University College London Hospitals.
Curr Opin Urol. 2020 Mar;30(2):213-217. doi: 10.1097/MOU.0000000000000711.
The aim of this article is to provide an overview of the current literature specific to surgery for localized penile cancer including novel reconstructive techniques.Centralization of penile cancer services in many European countries and in particular the United Kingdom has resulted in an increased proportion of men undergoing organ-sparing surgery (OSS) rather than partial or total penectomy. In this review, we focus on reconstructive techniques following surgery for the primary penile tumour.
The widespread adoption of penile preserving techniques in Europe and North America has shown both oncological safety as well as good cosmetic and functional outcomes. Recent evidence has suggested that narrower surgical margins do not affect overall cancer-specific survival or local recurrence rates. Therefore, excellent cosmetic and functional outcomes can be achieved using techniques such as glans resurfacing using split-thickness skin grafts, dorsal or ventral V-Y skin advancement and urethral centralization after partial penectomy. For patients requiring more radical surgery such as total penectomy, phallic reconstruction is a suitable option using free flaps or pedicled flaps.
The use of OSS has transformed the lives of penile cancer patients who can avoid the significant clinical and psychological consequences of more radical surgical treatments. Careful case selection and preoperative counselling is advised prior to reconstructive techniques. Close postoperative clinical surveillance is necessary for early detection of local recurrence.
本文旨在概述局部阴茎癌手术相关的最新文献,包括新型重建技术。许多欧洲国家,特别是英国,集中开展阴茎癌服务,这导致越来越多的男性接受保器官手术(OSS),而不是部分或全部阴茎切除术。在本次综述中,我们重点关注原发性阴茎肿瘤手术后的重建技术。
在欧洲和北美,广泛采用保阴茎技术,已显示出良好的肿瘤安全性以及美容和功能效果。最近的证据表明,更窄的手术切缘不会影响癌症特异性总生存率或局部复发率。因此,采用诸如使用薄断层皮片进行龟头再造、背侧或腹侧 V-Y 皮瓣推进以及部分阴茎切除术后尿道集中等技术,可实现极好的美容和功能效果。对于需要更激进手术的患者,如全阴茎切除术,游离皮瓣或带蒂皮瓣的阴茎重建是一种合适的选择。
OSS 的使用改变了阴茎癌患者的生活,使他们能够避免更激进的手术治疗带来的重大临床和心理后果。在进行重建技术之前,建议进行仔细的病例选择和术前咨询。术后密切的临床监测对于早期发现局部复发是必要的。