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差异表达基因探索器(DrEdGE):一种用于生成基因表达数据集交互式在线可视化的工具。

Differential Expression Gene Explorer (DrEdGE): a tool for generating interactive online visualizations of gene expression datasets.

机构信息

Department of Biology.

School of Information and Library Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

出版信息

Bioinformatics. 2020 Apr 15;36(8):2581-2583. doi: 10.1093/bioinformatics/btz972.

Abstract

SUMMARY

Differential Expression Gene Explorer (DrEdGE) is a web-based tool that guides genomicists through easily creating interactive online data visualizations, which colleagues can query according to their own conditions to discover genes, samples or patterns of interest. We demonstrate DrEdGE's features with three example websites generated from publicly available datasets-human neuronal tissue, mouse embryonic tissue and Caenorhabditis elegans whole embryos. DrEdGE increases the utility of large genomics datasets by removing technical obstacles to independent exploration.

AVAILABILITY AND IMPLEMENTATION

Freely available at http://dredge.bio.unc.edu.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

差异表达基因探索器(DrEdGE)是一个基于网络的工具,指导基因组学家轻松创建交互式在线数据可视化,同事可以根据自己的条件查询这些可视化,以发现感兴趣的基因、样本或模式。我们使用三个示例网站展示了 DrEdGE 的功能,这些示例网站是从公开可用的数据集-人类神经元组织、小鼠胚胎组织和秀丽隐杆线虫整个胚胎中生成的。DrEdGE 通过消除独立探索的技术障碍,提高了大型基因组数据集的实用性。

可用性和实现

可在 http://dredge.bio.unc.edu 免费获得。

补充信息

补充数据可在 Bioinformatics 在线获得。

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