Department of Ophthalmology, Keio University School of Medicine , Tokyo, Japan.
Department of Ophthalmology, Wada Eye Clinic , Chiba, Japan.
Curr Eye Res. 2020 Jul;45(7):782-788. doi: 10.1080/02713683.2019.1700530. Epub 2020 Jan 3.
This study aimed to prospectively assess tear dynamics in soft contact lens-induced dry eye while wearing and after removing the soft contact lenses.
We analyzed 17 right eyes of soft contact lens users at Wada Eye Clinic (11 men, 6 women; mean age: 36.8 ± 8.3 years; range: 24-57 years). Participants were divided into two groups depending on presence of dry eye symptoms. Video interferometry was used to observe tear dynamics while wearing and after removing soft contact lenses. Interference images focusing on tear spread and interference fringe were compared between groups.
This study included 10 symptomatic and 7 asymptomatic eyes. Considering the symptomatic eyes, while wearing soft contact lenses, 8 eyes showed poor tear spread and multicolor interference fringe, i.e., swift flow of multicolor interference waves after a grayish monochromatic band-color after a blink, but 8 and 10 eyes showed good tear spread and a grayish monochromatic interference fringe when soft contact lenses were removed, respectively. As for asymptomatic eyes, 6 eyes exhibited good tear spread and a grayish monochromatic interference fringe while wearing soft contact lenses and after removing soft contact lenses.
soft contact lens-induced dry eye was associated with tear dynamics only while wearing soft contact lenses. Observation of tear film dynamics in eyes with soft contact lenses could facilitate the understanding of dry eye-related symptoms.
本研究旨在前瞻性评估软性隐形眼镜引起的干眼症患者在佩戴和移除软性隐形眼镜时的泪液动力学变化。
我们分析了和田眼科诊所(Wada Eye Clinic)的 17 只右眼(11 名男性,6 名女性;平均年龄:36.8±8.3 岁;范围:24-57 岁)。根据是否存在干眼症状,将参与者分为两组。使用视频干涉仪观察佩戴和移除软性隐形眼镜时的泪液动力学。比较两组之间的泪膜扩展和干涉条纹的干涉图像。
本研究包括 10 只症状性眼和 7 只无症状眼。对于症状性眼,在佩戴软性隐形眼镜时,8 只眼显示出较差的泪膜扩展和多色干涉条纹,即在眨眼后出现灰色单色带色后,多色干涉波迅速流动,但 8 只眼和 10 只眼在移除软性隐形眼镜后分别显示出良好的泪膜扩展和灰色单色干涉条纹。对于无症状眼,6 只眼在佩戴和移除软性隐形眼镜时均显示出良好的泪膜扩展和灰色单色干涉条纹。
软性隐形眼镜引起的干眼症仅与佩戴软性隐形眼镜时的泪液动力学有关。观察佩戴软性隐形眼镜时的泪膜动力学有助于理解与干眼症相关的症状。