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成人在一般医疗实践中的疫苗接种。

Vaccination of Adults in General Medical Practice.

机构信息

Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison, WI; City of Milwaukee Health Department, WI.

Emory University School of Medicine, Atlanta, GA.

出版信息

Mayo Clin Proc. 2020 Jan;95(1):169-183. doi: 10.1016/j.mayocp.2019.02.024.

Abstract

In vaccinating adults, clinicians face 2 types of challenges: (1) staying current on recommendations for influenza, pneumococcal, hepatitis A and B, zoster, and other vaccines and (2) addressing systemic barriers to implementing practices that increase vaccination rates. Although adult immunization rates remain suboptimal, there has been much good news in adult vaccination recently. New high-dose and adjuvanted influenza vaccines help improve immune response and may reduce influenza complications in older adults. The new recombinant zoster vaccine offers significantly more efficacy against zoster outbreaks and postherpetic neuralgia than zoster vaccine live. Pertussis vaccine given during the third trimester of pregnancy may prevent between 50% and 90% of pertussis infections in infants. Shorter time for completion (1 vs 6 months) of new, adjuvanted hepatitis B vaccine may increase adherence. Clinicians can address systemic barriers to increasing vaccination rates in their clinics and health care systems by following the Centers for Disease Control and Prevention's Standards for Adult Immunization Practice. Clinicians can help increase vaccination rates by writing standing orders and by advocating for nurses or medical assistants to receive training and protected time for assessing and documenting vaccination histories and administration. Strong recommendations that presume acceptance of vaccination are effective with most patients. Communication techniques similar to motivational interviewing can help with vaccine-hesitant patients. Clinicians, as experts on providing preventive services, can educate community leaders about the benefits of immunization and can inform vaccine experts about challenges of implementing vaccination recommendations in clinical practice and strategies that can work to raise vaccination rates.

摘要

在为成年人接种疫苗时,临床医生面临着 2 种挑战:(1)及时了解流感、肺炎球菌、甲型和乙型肝炎、带状疱疹和其他疫苗的建议;(2)解决实施提高疫苗接种率的实践所面临的系统性障碍。尽管成人免疫接种率仍然不理想,但最近成人疫苗接种方面有很多好消息。新型高剂量和佐剂流感疫苗有助于提高免疫反应,并可能减少老年人的流感并发症。新型重组带状疱疹疫苗在预防带状疱疹爆发和带状疱疹后神经痛方面的疗效明显优于带状疱疹活疫苗。在妊娠第三个月接种百日咳疫苗,可能会预防 50%至 90%的婴儿百日咳感染。新的、佐剂的乙型肝炎疫苗完成接种所需的时间更短(1 个月与 6 个月),可能会提高接种的依从性。临床医生可以通过遵循疾病预防控制中心的成人免疫接种实践标准,来解决其诊所和医疗保健系统中增加疫苗接种率的系统性障碍。临床医生可以通过制定常规医嘱,并倡导护士或医疗助理接受培训并获得评估和记录疫苗接种史和接种疫苗的时间,来帮助提高疫苗接种率。对大多数患者有效且假设其接受疫苗接种的强烈建议是有效的。类似于动机性访谈的沟通技巧可以帮助那些对接种犹豫不决的患者。作为提供预防服务的专家,临床医生可以向社区领导人宣传免疫接种的益处,并向疫苗专家通报在临床实践中实施疫苗接种建议所面临的挑战,以及可以提高疫苗接种率的策略。

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