Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University School of Medicine, Baltimore, Md.
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Md.
J Vasc Surg. 2020 Aug;72(2):611-621.e5. doi: 10.1016/j.jvs.2019.10.075. Epub 2020 Jan 2.
Despite guidelines cautioning against the use of endovascular peripheral vascular interventions (PVI) for claudication, more than 1.3 million PVI procedures are performed annually in the United States. We aimed to describe national rates of PVI for claudication, and identify patient and county-level risk factors associated with a high rate of PVI.
We used the Medicare claims database to identify all Medicare beneficiaries with a new diagnosis of claudication between January 2015 and June 2017. A hierarchical logistic regression model accounting for patient age, sex, comorbidities; county region and setting; and a patient race-county median income interaction was used to assess the associations of race and income with a high PVI rate.
We identified 1,201,234 patients with a new diagnosis of claudication for analysis. Of these, 15,227 (1.27%) underwent a PVI. Based on hierarchical logistic regression accounting for patient and county-level factors, black patients residing in low-income counties had a significantly higher odds of undergoing PVI than their white counterparts (odds ratio [OR], 1.30; 95% confidence interval [CI], 1.20-1.40), whereas the odds of PVI for black versus white patients was similar in high-income counties (OR, 1.06; 95% CI, 0.99-1.14). PVI rates were higher for low versus high-income counties in both the black (OR, 1.46; 95% CI, 1.31-1.64) and white (OR, 1.19; 95% CI, 1.12-1.27) groups. There were no significant associations of Hispanic, Asian, North American native, or other races with PVI in either low- or high-income counties after risk adjustment (all P ≥ .09).
In the Medicare population, the mean rate of PVI of 12.7 per 1000 claudication patients varies significantly based on race and income. Our data suggest there are racial and socioeconomic differences in the treatment of claudication across the United States.
尽管指南警告不要将血管内外周血管介入 (PVI) 用于跛行,但美国每年仍进行超过 130 万例 PVI 手术。我们旨在描述 PVI 用于跛行的全国发生率,并确定与高 PVI 发生率相关的患者和县级风险因素。
我们使用医疗保险索赔数据库,确定 2015 年 1 月至 2017 年 6 月期间患有新诊断跛行的所有医疗保险受益人。使用分层逻辑回归模型,考虑患者年龄、性别、合并症;县区域和环境;以及患者种族-县中位数收入相互作用,评估种族和收入与高 PVI 率的关联。
我们确定了 1,201,234 名患有新诊断跛行的患者进行分析。其中,15,227 人(1.27%)接受了 PVI。基于考虑患者和县级因素的分层逻辑回归,居住在低收入县的黑人患者接受 PVI 的可能性明显高于其白人同龄人(优势比 [OR],1.30;95%置信区间 [CI],1.20-1.40),而黑人患者接受 PVI 的可能性与白人患者在高收入县相似(OR,1.06;95% CI,0.99-1.14)。在黑人和白人患者中,低收入县与高收入县相比,PVI 率均较高(OR,1.46;95% CI,1.31-1.64 和 OR,1.19;95% CI,1.12-1.27)。在风险调整后,无论是低收入县还是高收入县,西班牙裔、亚洲人、北美原住民或其他种族与 PVI 均无明显关联(所有 P ≥.09)。
在 Medicare 人群中,12.7 例/1000 例跛行患者的 PVI 平均发生率因种族和收入而异。我们的数据表明,美国在治疗跛行方面存在种族和社会经济差异。