Rohrer M J, Michelotti M C, Nahrwold D L
Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611.
Ann Surg. 1988 Nov;208(5):554-7. doi: 10.1097/00000658-198811000-00002.
The efficacy of routine screening coagulation tests was studied to identify occult coagulopathies in patients prior to elective general and vascular surgery procedures. The efficacy of screening tests was compared to that of indicated tests performed for predefined clinical indications, which were elicited by history and physical examination and a detailed coagulation history questionnaire. Tests were prothrombin time (PT), partial thromboplastin time (PTT), platelet count (PC), and bleeding time (BT). Of 514 screening tests done in the 282 patients, 4.1% were abnormal, but none of them identified a clinically significant coagulopathy. Of the 605 indicated tests, 7.4% were abnormal, and all significant coagulopathies were found in this group. The study shows that preoperative screening tests for coagulopathies not suspected on the basis of detailed clinical information are unnecessary and should not be done. In the authors' institution 46% of screening coagulation tests could be eliminated.
对择期普通外科和血管外科手术患者进行常规筛查凝血试验,以确定隐匿性凝血病的疗效进行了研究。将筛查试验的疗效与针对预先定义的临床指征进行的针对性试验的疗效进行比较,这些临床指征是通过病史、体格检查和详细的凝血病史问卷得出的。检测项目包括凝血酶原时间(PT)、部分凝血活酶时间(PTT)、血小板计数(PC)和出血时间(BT)。在282例患者中进行的514项筛查试验中,4.1%异常,但均未发现具有临床意义的凝血病。在605项针对性试验中,7.4%异常,所有具有临床意义的凝血病均在该组中被发现。该研究表明,对于根据详细临床信息未怀疑的凝血病进行术前筛查试验是不必要的,不应进行。在作者所在机构,46%的筛查凝血试验可以取消。