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对于接受择期扁桃体切除术和/或腺样体切除术的健康儿童,是否需要进行常规术前凝血筛查试验(凝血酶原时间PT/活化部分凝血活酶时间PTT)。

The need for routine pre-operative coagulation screening tests (prothrombin time PT/partial thromboplastin time PTT) for healthy children undergoing elective tonsillectomy and/or adenoidectomy.

作者信息

Asaf T, Reuveni H, Yermiahu T, Leiberman A, Gurman G, Porat A, Schlaeffer P, Shifra S, Kapelushnik J

机构信息

Pediatric Hemato-Oncology Unit, Soroka University Medical Center, P.O. Box 151, Beer-Sheva 84101, Israel.

出版信息

Int J Pediatr Otorhinolaryngol. 2001 Dec 1;61(3):217-22. doi: 10.1016/s0165-5876(01)00574-2.

Abstract

In some medical centers, the routine pre-operative evaluation of healthy children undergoing elective tonsillectomy and/or adenoidectomy (T and A) includes coagulation screening tests (PT, prothrombin Time; PTT, partial thromboplastin time; and INR, international normalized ratio). In this retrospective study, we determined whether there is a positive correlation between prolonged PT/PTT/INR tests in healthy children, with no prior medical history of coagulation problems, and bleeding during surgery and/or bleeding in the month following surgery. We reviewed the records of 416 elective T and A surgeries performed at the Soroka University Medical Center in Beer-Sheva, Israel, over the course of 1999. One hundred and twenty-one (29.1%) patients had preoperative prolonged PT values but only four (3.3%) of these patients experienced light bleeding during surgery. Seven (5.8%) of the 121 patients with prolonged PT tests experienced bleeding episodes during the 1st month subsequent to the surgery. Of the 65 (15.6%) patients who had prolonged pre-operative INR values, only three (4.6%) experienced light bleeding during surgery. Two (3.1%) patients with prolonged INR values experienced light bleeding during the 1st month subsequent to surgery. Sixty-one (14.7%) patients had prolonged first preoperative PTT values, only five of whom (8.2%) experienced light bleeding during surgery. Two (3.3%) of the 61 with prolonged PTT values experienced light bleeding during the 1st month subsequent to surgery. We therefore concluded that pre-operative coagulation screening tests provide low sensitivity and low bleeding predictive value. As such, routine coagulation tests before T &A are not indicated unless a medical history of bleeding tendency is suspected.

摘要

在一些医疗中心,对计划接受扁桃体切除术和/或腺样体切除术(T&A)的健康儿童进行的常规术前评估包括凝血筛查试验(PT,凝血酶原时间;PTT,部分凝血活酶时间;INR,国际标准化比值)。在这项回顾性研究中,我们确定了在无凝血问题既往病史的健康儿童中,PT/PTT/INR试验延长与手术期间出血和/或术后一个月内出血之间是否存在正相关。我们回顾了1999年期间在以色列贝尔谢巴的索罗卡大学医学中心进行的416例择期T&A手术的记录。121例(29.1%)患者术前PT值延长,但这些患者中只有4例(3.3%)在手术期间出现轻度出血。121例PT试验延长的患者中有7例(5.8%)在术后第一个月出现出血事件。在65例(15.6%)术前INR值延长的患者中,只有3例(4.6%)在手术期间出现轻度出血。2例(3.1%)INR值延长的患者在术后第一个月出现轻度出血。61例(14.7%)患者术前首次PTT值延长,其中只有5例(8.2%)在手术期间出现轻度出血。61例PTT值延长的患者中有2例(3.3%)在术后第一个月出现轻度出血。因此,我们得出结论,术前凝血筛查试验的敏感性和出血预测价值较低。因此,除非怀疑有出血倾向病史,否则不建议在T&A术前进行常规凝血试验。

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