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口服水解蛋壳膜对健康中年成年人毛发、皮肤和指甲外观的影响:一项随机、双盲、安慰剂对照的临床试验。

The effect of oral hydrolyzed eggshell membrane on the appearance of hair, skin, and nails in healthy middle-aged adults: A randomized double-blind placebo-controlled clinical trial.

机构信息

Health Professions Division, Department of Health and Human Performance, College of Health Care Sciences, Nova Southeastern University, Davie, FL, USA.

Department of Human Environmental Studies, Central Michigan University, Mount Pleasant, MI, USA.

出版信息

J Cosmet Dermatol. 2020 Jun;19(6):1463-1472. doi: 10.1111/jocd.13275. Epub 2020 Jan 6.

Abstract

BACKGROUND

Many over the counter and consumer packaged goods are promoted to enhance the appearance of hair, skin, and nails for the consumer. Nutrition is a major factor in affecting the health and appearance of hair, skin, and nails. In addition to how one eats, dietary supplementation may play a role in overall health and in the physical appearance.

AIMS

It was the aim of this study to objectively and subjectively evaluate the impacts of a nutritional intervention as compared to placebo on the appearances of hair, skin, and nails in healthy middle-aged adults.

METHODS

Randomized, double-blind placebo-controlled study with 88 subjects randomized evenly to Study Product (BiovaBio™ 450 mg/d, n = 44) or Placebo (n = 44) for 12-weeks. Outcome tests included TrichoScan HD (hair), Canfield Visia -CR (skin), modified FACE-Q (skin), and anchored Likert Scales (nails).

RESULTS

Oral hydrolyzed eggshell membrane ingestion was associated with a significant improvement in facial skin appearance in crow's feet in 4 weeks and skin tone in 8 weeks, with significant impact on hair thickness, reduction in hair breakage and improvement in hair growth at 4, 8, and 12 weeks. There were no observed subjective improvements for nails (appearance, strength or growth).

CONCLUSIONS

Oral supplementation of 450 mg/d hydrolyzed eggshell membrane for 12 weeks is associated with improvement in the appearance of facial skin and hair.

摘要

背景

许多非处方和消费者包装产品都被宣传为可改善头发、皮肤和指甲的外观,供消费者使用。营养是影响头发、皮肤和指甲健康和外观的主要因素。除了饮食方式外,膳食补充剂可能在整体健康和身体外观方面发挥作用。

目的

本研究旨在客观和主观地评估营养干预与安慰剂相比对健康中年成年人的头发、皮肤和指甲外观的影响。

方法

采用随机、双盲、安慰剂对照研究,88 名受试者随机分为研究产品(BiovaBio™ 450mg/d,n=44)或安慰剂(n=44)组,干预 12 周。结局测试包括 TrichoScan HD(头发)、Canfield Visia-CR(皮肤)、改良 FACE-Q(皮肤)和锚定李克特量表(指甲)。

结果

口服水解蛋壳膜摄入与 4 周时鱼尾纹的面部皮肤外观和 8 周时皮肤色调显著改善相关,4、8 和 12 周时头发厚度增加、头发断裂减少和头发生长改善具有显著影响。指甲(外观、强度或生长)无明显的主观改善。

结论

口服补充 450mg/d 水解蛋壳膜 12 周与面部皮肤和头发外观改善有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6dd/7418556/ffe4655dac8c/JOCD-19-1463-g001.jpg

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