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巨大多形性纤维腺瘤的外科治疗:减少皮肤的肿瘤切除术和即刻乳房重建:单中心经验。

Surgical management of giant juvenile fibroadenoma with skin reducing tumor resection and immediate breast reconstruction: A single-center experience.

机构信息

Department of Plastic and Reconstructive Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

J Surg Oncol. 2020 Mar;121(3):441-446. doi: 10.1002/jso.25828. Epub 2020 Jan 6.

DOI:10.1002/jso.25828
PMID:31907948
Abstract

BACKGROUND AND OBJECTIVES

Giant juvenile fibroadenoma (GJF) is a rare benign tumor that disfiguring affects the breast shape and quality of life of patients. This study aimed to report the experience of GJF management.

METHODS

A Wise-pattern skin reducing tumor resection followed by immediate breast reconstruction with a dermal flap pocket was used. The long-term outcomes were assessed retrospectively by BREAST-Q questionnaire from 2008 to 2018.

RESULTS

The study included eight patients with GJF. All patients achieved satisfactory results without severe complications. The BREAST-Q revealed that postoperative scores for satisfaction with breasts (69.3 ± 17.6) and sexual wellbeing (62.3 ± 27.6) were higher than the normative scores. The psychosocial wellbeing (69.7 ± 14.6) and physical wellbeing-chest (86.8 ± 13.0) scores were slightly lower than the normative scores.

CONCLUSION

Although GJF is a benign tumor, it should be surgically removed. And the Wise-pattern skin reducing tumor resection with immediate breast reconstruction is a proper way to improve patients' satisfaction with breast size and shape and quality of life.

摘要

背景与目的

巨大型幼年性纤维腺瘤(Giant juvenile fibroadenoma,GJF)是一种罕见的良性肿瘤,会严重影响患者的乳房形状和生活质量。本研究旨在报告 GJF 管理的经验。

方法

采用 Wise 式皮肤缩减肿瘤切除术,随后立即进行皮瓣袋乳房重建。回顾性评估 2008 年至 2018 年期间使用 BREAST-Q 问卷的长期结果。

结果

本研究纳入了 8 例 GJF 患者。所有患者均获得了满意的结果,无严重并发症。BREAST-Q 显示,术后乳房满意度(69.3±17.6)和性健康(62.3±27.6)评分高于常模评分。社会心理健康(69.7±14.6)和胸部身体健康(86.8±13.0)评分略低于常模评分。

结论

尽管 GJF 是一种良性肿瘤,但仍应手术切除。Wise 式皮肤缩减肿瘤切除术联合即刻乳房重建是改善患者对乳房大小和形状以及生活质量满意度的一种恰当方法。

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Surgical management of giant juvenile fibroadenoma with skin reducing tumor resection and immediate breast reconstruction: A single-center experience.巨大多形性纤维腺瘤的外科治疗:减少皮肤的肿瘤切除术和即刻乳房重建:单中心经验。
J Surg Oncol. 2020 Mar;121(3):441-446. doi: 10.1002/jso.25828. Epub 2020 Jan 6.
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引用本文的文献

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Juvenile Fibroadenoma Detected at 2 Years and Rapid Growth at Thelarche: Case Report and Literature Review.2岁时发现的青少年纤维腺瘤及青春期乳房发育时的快速生长:病例报告与文献综述
Breast Cancer (Auckl). 2025 Sep 6;19:11782234241306209. doi: 10.1177/11782234241306209. eCollection 2025.
2
"Autologous Breast Dermal Filler": A Novel Technique for Breast Reconstruction After Nipple- or Skin-Sparing Mastectomy in Pubertal Gigantomastia.“自体乳房真皮填充剂”:青春期巨乳症患者行保留乳头或皮肤的乳房切除术后乳房重建的新技术
Aesthetic Plast Surg. 2025 Jan;49(1):205-210. doi: 10.1007/s00266-024-04207-7. Epub 2024 Jul 16.