Moroi R, Yamazaki K, Hirota T, Watanabe S, Kataoka K, Ichinose M
Research Institute, Daiichi Seiyaku Co., Ltd., Tokyo, Japan.
Arzneimittelforschung. 1988 Jul;38(7A):953-9.
N2-[(N-acetylmuramoyl)-L-alanyl-D-isoglutaminyl-N6-stearoyl-L-lysine (MDP-Lys(L18), muroctasin) was studied to clarify its chemical structure and physico-chemical properties. The chemical structure of MDP-Lys(L18) was confirmed by UV, IR, NMR and MS analyses as well as by elemental analysis. The physico-chemical properties were investigated by thermal analysis, powder X-ray analysis, ionization constant measurement, high-performance liquid and thin-layer chromatography.