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Cochrane系统评价关于用于治疗中风的中药的综述

Overview of Cochrane reviews on Chinese herbal medicine for stroke.

作者信息

Wei Maoling, Wang Deren, Kang Deying, Lee Myeong Soo, Choi Tae-Young, Ang Lin, Song Eunhye

机构信息

The Center for Evidence-based Medicine and Clinical Epidemiology, West China Hospital, Sichuan University, Chengdu, China.

Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Integr Med Res. 2020 Mar;9(1):5-9. doi: 10.1016/j.imr.2019.11.009. Epub 2019 Nov 22.

DOI:10.1016/j.imr.2019.11.009
PMID:31908922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6938924/
Abstract

BACKGROUND

Stroke is a major health issue worldwide. Since Chinese herbal medicine is widely used for the treatment of stroke, there is a need to evaluate its efficacy as an alternative treatment option. The aim of this paper is to carry out an overview of Chinese herbal medicine for the treatment of stroke by summarizing and evaluating all existing Cochrane reviews.

METHODS

The Cochrane Database of Systematic Reviews was searched from its inception date to August 2019 using "stroke" and "herbal medicine" or "traditional medicine" as search terms. For the methodological quality assessment of the Cochrane reviews, the Assessment of Multiple Systematic Reviews (AMSTAR) tool was used.

RESULTS

Eight Cochrane reviews that evaluated the efficacy of herbal medicine for the treatment of stroke were included in this overview. There were 71 randomized controlled trials, with 5770 patients in total. The AMSTAR scores of the Cochrane reviews included in this study ranged from 9 to 11 with a mean score of 10. Three reviews met all the 11-item criteria of the AMSTAR. All reviews presented potential efficacy of herbal medicine for stroke treatment in terms of improvement of neurological deficit.

CONCLUSION

This overview reveals the potential efficacy of herbal medicines for the treatment of stroke in terms of neurological deficit improvement. However, due to the high risk of bias in the reviews' studies, an affirmative conclusion for the recommendation of herbal medicine for clinical practice could not be drawn.

摘要

背景

中风是全球主要的健康问题。由于中草药被广泛用于中风治疗，因此有必要评估其作为替代治疗方案的疗效。本文旨在通过总结和评估所有现有的Cochrane综述，对中草药治疗中风进行概述。

方法

以“中风”和“草药”或“传统医学”为检索词，检索Cochrane系统评价数据库从创建至2019年8月的文献。对于Cochrane综述的方法学质量评估，使用了多重系统评价评估（AMSTAR）工具。

结果

本概述纳入了八项评估草药治疗中风疗效的Cochrane综述。共有71项随机对照试验，总计5770例患者。本研究纳入的Cochrane综述的AMSTAR评分范围为9至11，平均评分为10。三项综述符合AMSTAR的所有11项标准。所有综述均表明，草药在改善神经功能缺损方面对中风治疗具有潜在疗效。

结论

本概述揭示了草药在改善神经功能缺损方面治疗中风的潜在疗效。然而，由于综述研究中存在较高的偏倚风险，无法得出在临床实践中推荐草药的肯定性结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5296/6938924/17840a8eb061/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5296/6938924/17840a8eb061/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5296/6938924/17840a8eb061/gr1.jpg

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针灸和中药联合传统康复治疗对脑卒中后功能恢复的影响：一项回顾性队列研究
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