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犬类繁殖力:特殊性状选择的后果。

Canine fertility: The consequences of selection for special traits.

机构信息

Department of Veterinary Medicine - DIMEVET, University of Milan, Milano, Italy.

Ambulatorio Beccaglia, Lissone, Italy.

出版信息

Reprod Domest Anim. 2020 Jul;55 Suppl 2:4-9. doi: 10.1111/rda.13586. Epub 2020 Jan 8.

Abstract

Pedigree dogs and cats are bred aiming to conform breed standards with very poor consideration for breeding stock fertility. At the same time, the genetic asset underlining reproductive traits could be effectively analysed like in other species under selection. The definition of selection targets is very important in breeding protocols determination. The aim of the present work is to present an overview of the different correlations between reproduction and genetics, starting from selection procedure and inbreeding coefficient moving to genomic and the application of SNPs and GWAS on population study and identification of genes involved in phenotypical variation of reproductive traits in dogs. Particular relevance has been given to the concept of inbreeding which effects on canine reproduction have been presented. The use of genomic information in inbreeding coefficient calculation can be considered an improved effective procedure in the evaluation of the genetic variability loss in canine population and its negative effects on reproductive traits.

摘要

pedigree 犬猫的繁殖是为了使它们符合品种标准,而对繁殖种群的生育力考虑甚少。同时,像其他受选择影响的物种一样,可以有效地分析突出生殖特征的遗传资产。选择目标的定义在确定繁殖方案中非常重要。本工作的目的是从选择程序和近交系数开始,概述繁殖和遗传学之间的不同关系,进而讨论基因组和 SNP 及 GWAS 的应用,以及在群体研究中确定与犬生殖性状表型变异相关的基因。特别关注了近交的概念,介绍了其对犬繁殖的影响。在近交系数的计算中使用基因组信息,可以被认为是评估犬种群遗传变异性丧失及其对生殖性状的负面影响的一种改进的有效方法。

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