Division of Pediatric Nephrology and Hypertension, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3901 Beaubien St, Detroit, MI, 48201, USA.
Paediatr Drugs. 2020 Feb;22(1):13-20. doi: 10.1007/s40272-019-00377-z.
Severe hypertension in children may result in life-threatening complications. Although there has not been extensive research in this area in children, and recommendations are mostly derived from adult data, in the last few years, there have been more pediatric studies on the safety and effectiveness of antihypertensives. The clinical presentation of a child with severe hypertension varies and may be completely asymptomatic or include signs and symptoms of end-organ damage. Treatment of a child with severe hypertension is emergent and should be done concomitantly with the evaluation.
儿童重度高血压可能导致危及生命的并发症。虽然在儿童中这方面的研究还不够广泛,且推荐意见主要来源于成人数据,但在过去几年中,已经有更多关于儿童降压药安全性和有效性的研究。患有重度高血压的儿童临床表现各异,可能完全无症状,也可能包括靶器官损害的体征和症状。儿童重度高血压的治疗是紧急的,应与评估同时进行。