Zaman Behrooz, Mohseni Masood, Noorizad Samad, Jalali Motlagh Soudabeh, Amiraslani Taymaz, Sayyahi Monal
School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Pain Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Anesth Pain Med. 2024 Oct 29;14(5):e151582. doi: 10.5812/aapm-151582. eCollection 2024 Oct.
Intraoperative bleeding is one of the major challenges in rhinoplasty.
This study aimed to evaluate the effect of pressure-controlled ventilation (PCV) versus volume-controlled ventilation (VCV) modes on intraoperative bleeding during rhinoplasty.
In a double-blinded randomized clinical trial, 58 candidates for rhinoplasty were randomly assigned to the PCV or VCV groups. Anesthesia was induced and maintained using the same total intravenous anesthesia (TIVA) method in both groups. The amount of bleeding was assessed by counting blood-soaked gauze and measuring the content of the suctioned fluid. Additionally, bleeding in the surgical field was assessed by the surgeon using the Boezaart criterion.
The mean intraoperative bleeding volume was 30 ± 45 mL in the PCV group and 100 ± 120 mL in the VCV group (P < 0.001). According to logistic regression analysis, the odds of experiencing moderately severe or severe bleeding in the VCV group were 5.4 times higher than in the PCV group. After adjusting for confounding variables, the odds ratio increased to 26.8 (95% CI = 1.2, 59.3).
The results of the study suggest that the pressure-controlled mode may lead to lower intraoperative bleeding compared to the volume-controlled mode. The decrease in peak airway pressure is likely a contributing factor to this observation.
术中出血是隆鼻手术中的主要挑战之一。
本研究旨在评估压力控制通气(PCV)与容量控制通气(VCV)模式对隆鼻手术中术中出血的影响。
在一项双盲随机临床试验中,58名隆鼻手术候选人被随机分配到PCV组或VCV组。两组均采用相同的全静脉麻醉(TIVA)方法诱导和维持麻醉。通过计算血浸纱布数量和测量吸引液含量来评估出血量。此外,外科医生使用Boezaart标准评估手术视野中的出血情况。
PCV组术中平均出血量为30±45 mL,VCV组为100±120 mL(P<0.001)。根据逻辑回归分析,VCV组发生中度严重或严重出血的几率比PCV组高5.4倍。在对混杂变量进行调整后,优势比增至26.8(95%CI=1.2,59.3)。
研究结果表明,与容量控制模式相比,压力控制模式可能导致术中出血更少。气道峰压降低可能是导致这一观察结果的一个因素。