Dottorini Lorenzo, Sarno Italo, Scopelliti Pasquale, Cotroneo Gianluca, Duluc Maribel, Iaculli Alessandro, Giuntini Nicola, Brena Federica, Nastasi Giuseppe
Oncology Unit, Medical Sciences Department, ASST Bergamo Est, Alzano Lombardo, BG 24022, Italy.
Cardiology Unit, Medical Sciences Department, ASST Bergamo Est, Alzano Lombardo, BG 24022, Italy.
Ecancermedicalscience. 2019 Nov 19;13:977. doi: 10.3332/ecancer.2019.977. eCollection 2019.
We report the case of an immunocompetent 65-year-old man affected by cutaneous squamous cell carcinoma (cSCC) with lung and biatrial metastatic localisation. In May 2018, the patient underwent lower limb amputation due to the finding of a large ulceration which upon biopsy was found to be a poorly differentiated squamous cell carcinoma (SCC), ulcerated, full-thickness infiltrating from the skin to the underlying bone tissue. After 1 month, a radiological restaging found multiple pulmonary localisations and a right-atrial metastatic localisation. The patient was then studied in-depth and a transesophageal echocardiogram found that the patient had two 2 and 5 cm metastatic localisations in the left atrium and a 3-cm metastatic localisation in the right atrium. Informed about the clinical situation and about the risks of a chemotherapeutic treatment, the patient decided not to start any treatment. This case represents, to our knowledge, the only case of a biatrial metastatic localisation from cSCC and is representative of how cardiac symptoms and signs in patients affected by this disease must be evaluated.
我们报告一例65岁免疫功能正常的男性患者，患有皮肤鳞状细胞癌（cSCC）并伴有肺和双心房转移。2018年5月，患者因发现一个大溃疡而接受下肢截肢手术，活检发现该溃疡为低分化鳞状细胞癌（SCC），呈溃疡状，全层浸润，从皮肤至下方骨组织。1个月后，影像学重新分期发现多处肺部转移和右心房转移。随后对患者进行深入检查，经食管超声心动图发现患者左心房有两个2厘米和5厘米的转移灶，右心房有一个3厘米的转移灶。在了解临床情况和化疗风险后，患者决定不开始任何治疗。据我们所知，该病例是cSCC双心房转移的唯一病例，代表了如何对患有这种疾病的患者的心脏症状和体征进行评估。
