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转移性皮肤鳞状细胞癌继发右心室流入道梗阻

Right ventricular inflow tract obstruction secondary to metastatic cutaneous squamous cell carcinoma.

作者信息

Hunter Jonathan Michael, Reid Angeline Louise, Stride Peter John, Dettrick Andrew

机构信息

Department of Medicine, Redcliffe Hospital, Brisbane, Queensland, Australia.

出版信息

BMJ Case Rep. 2012 Aug 18;2012:bcr2012006556. doi: 10.1136/bcr-2012-006556.

DOI:10.1136/bcr-2012-006556
PMID:22907856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3624482/
Abstract

We report the case of an immunocompetent 83-year-old man with metastatic neoplastic infiltration of the heart from primary squamous cell carcinoma (SCC) of the skin. Death was from cardiopulmonary collapse due to left ventricular failure with features of right ventricular inflow tract obstruction. Metastatic tumours involving the heart rarely originate from cutaneous SCC though have been reported in the literature in both immunocompetent and postrenal-transplant recipient patients. Most involve the pericardium and only rarely the endocardium or the myocardium. While the prognosis is generally poor, palliative radiotherapy may provide significant symptom relief. Cardiac metastases should be considered in patients with advanced cancer, especially when they show cardiac symptoms and signs.

摘要

我们报告了一例83岁免疫功能正常的男性病例,其心脏出现了源自皮肤原发性鳞状细胞癌(SCC)的转移性肿瘤浸润。患者死于心肺功能衰竭,原因是左心室衰竭并伴有右心室流入道梗阻的特征。累及心脏的转移性肿瘤很少起源于皮肤SCC,尽管在免疫功能正常的患者和肾移植受者中均有文献报道。大多数累及心包,很少累及心内膜或心肌。虽然总体预后较差,但姑息性放疗可能会显著缓解症状。晚期癌症患者应考虑心脏转移,尤其是当他们出现心脏症状和体征时。

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本文引用的文献

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A systematic review of worldwide incidence of nonmelanoma skin cancer.一项全球范围内非黑色素瘤皮肤癌发病率的系统回顾。
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Metastatic squamous cell carcinoma causing right ventricular outflow tract obstruction.转移性鳞状细胞癌导致右心室流出道梗阻。
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