Chikasue F, Yashiki M, Kojima T, Miyazaki T, Okamoto I, Ohtani M, Kodama K
Department of Legal Medicine, Hiroshima University School of Medicine, Japan.
Forensic Sci Int. 1988 Sep;38(3-4):173-83. doi: 10.1016/0379-0738(88)90164-8.
The cyanide distribution in five fatal cyanide poisonings was analyzed by the pyridine-pyrazolone method using a Conway diffusion cell. In order to study the effect of storage conditions on cyanide concentration in tissue samples, the cyanide concentrations were first measured immediately after collection of the samples at autopsy, then measured again after storage in a refrigerator (4 degrees C) or in a freezer (-20 degrees C) for periods ranging from 1 day to 3 weeks. Concentrations in all but three of the blood samples stored at 4 degrees C or -20 degrees C increased, with concentration ratios based on measurement made before and after storage ranging from 0.71 to 1.46. The concentrations in the liver, kidney, and brain samples either increased or decreased, with ratios of from 0.2 to 8.8. The concentrations in the stomach contents samples decreased rapidly at 4 degrees C, but hardly changed at all at -20 degrees C.
采用康威扩散池，运用吡啶 - 吡唑啉酮法分析了五例致命氰化物中毒案件中的氰化物分布情况。为研究储存条件对组织样本中氰化物浓度的影响，在尸检时样本采集后立即测量氰化物浓度，之后将样本分别储存在冰箱（4摄氏度）或冰柜（-20摄氏度）中1天至3周，再进行测量。储存在4摄氏度或 -20摄氏度的血液样本中，除三个样本外，其余样本的浓度均有所增加，储存前后测量的浓度比值在0.71至1.46之间。肝脏、肾脏和脑样本中的浓度有的增加，有的减少，比值在0.2至8.8之间。胃内容物样本在4摄氏度时浓度迅速下降，但在 -20摄氏度时几乎没有变化。
