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德国初级医疗保健中不合理抗生素处方决策的复杂现象:一项运用双加工理论的定性访谈研究

The complex phenomenon of dysrational antibiotics prescribing decisions in German primary healthcare: a qualitative interview study using dual process theory.

作者信息

Poss-Doering Regina, Kamradt Martina, Stuermlinger Anna, Glassen Katharina, Kaufmann-Kolle Petra, Andres Edith, Wensing Michel

机构信息

1Department of General Practice and Health Services Research, University Hospital Heidelberg, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany.

aQua Institut, Maschmuehlenweg 8-10, 37073 Goettingen, Germany.

出版信息

Antimicrob Resist Infect Control. 2020 Jan 6;9(1):6. doi: 10.1186/s13756-019-0664-6. eCollection 2020.

Abstract

BACKGROUND

Antibiotic prescription rates in primary care in Germany are moderate, but still considered too high. The ARena study (Sustainable reduction of antibiotic-induced antimicrobial resistance) was initiated to foster awareness and understanding of the growing challenge and promotes rational antibiotics use for acute, non-complicated and self-limiting infections.

METHODS

The present study was performed as part of the process evaluation of the ARena study. Interviews were conducted with a purposive sample of physicians participating in the ARena study to identify factors relevant to primary care physicians' decision-making when prescribing antibiotics for acute non-complicated infections. Generated data were audio-recorded. Pseudonymized verbatim transcripts were coded using a pre-defined framework. The Dual Process Theory was applied to provide understanding of individual health professional factors that induce dysrational prescribing decisions.

RESULTS

Based on medical as well as non-medical considerations, physicians developed habits in decision making on antibiotics prescribing. They acknowledged inadequate antibiotics prescribing for acute, non-complicated infections in situations involving uncertainty regarding diagnosis, prognosis, continuity of care, patient expectations and when not knowing the patient. Educative efforts empowered physicians to override habitual prescribing. A theory-driven model provides transparency as to how dysrational prescribing decisions occur and suggests remedy by providing new experiences and new recognizable patterns through educative efforts.

CONCLUSIONS

Educational interventions may only change prescribing behaviours if they result in active rational rather than routine-based decision-making on antibiotics prescribing.

TRIAL REGISTRATION

ISRCTN, ISRCTN58150046.

摘要

背景

德国初级医疗保健中的抗生素处方率处于中等水平,但仍被认为过高。发起了ARena研究(可持续降低抗生素诱导的抗菌药物耐药性),以提高对这一日益严峻挑战的认识和理解,并促进对急性、非复杂性和自限性感染合理使用抗生素。

方法

本研究作为ARena研究过程评估的一部分进行。对参与ARena研究的医生进行了有目的抽样访谈,以确定在为急性非复杂性感染开抗生素处方时与初级保健医生决策相关的因素。生成的数据进行了录音。使用预定义框架对匿名逐字记录进行编码。应用双过程理论来理解导致不合理处方决策的个体健康专业因素。

结果

基于医学和非医学考虑,医生在抗生素处方决策中形成了习惯。他们认识到在诊断、预后、连续护理、患者期望以及不了解患者等存在不确定性的情况下,对急性非复杂性感染的抗生素处方不足。教育努力使医生能够超越习惯性处方。一个理论驱动的模型揭示了不合理处方决策是如何发生的,并通过教育努力提供新的经验和新的可识别模式来提出补救措施。

结论

教育干预可能只有在导致对抗生素处方进行积极合理而非基于常规的决策时,才会改变处方行为。

试验注册

ISRCTN,ISRCTN58150046。

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