Mangani Sebastiano, Sauro Francesca, Ponticelli Alfredo
Department of Pediatrics, Clinica Sanatrix, Naples, Italy.
Turk J Urol. 2019 Dec 18;46(2):146-151. doi: 10.5152/tud.2019.19147. Print 2020 Mar.
The aim of the present study was to examine the relationship between nocturnal enuresis (NE) of childhood and nocturia of parents.
The study was conducted across the network of general pediatricians of the ASL NA 1 of Naples, Italy. All the children with NE and their mothers were invited to attend the clinic for the study. Data were collected by personal interview. A 5-day bladder diary was collected from all the children. The mothers with nocturia were given a 3-day frequency-volume chart to assess the presence of nocturnal polyuria or reduced bladder capacity. Both children and mothers underwent a bladder ultrasound scan to measure the bladder wall thickness.
A total of 224 mothers (aged between 23 and 45 years, average 33.3±4.1 years) and their 225 children (aged between 7 and 13 years, average 8.35±1.81 years) were investigated. Of the 224 mothers, 90 (40%) had nocturia, of which 55 (61%) clearly remembered that they had suffered from NE in childhood. Only 4 (11%) out of the 35 women without nocturia had NE (p<0.001). Children with persistence of NE beyond 11 years were more likely to have a parent with nocturia. Children with non-monosymptomatic NE were more likely to have mothers with nocturia (odds ratio (OR) 1.7, 95% confidence interval (CI) 1.2-7.1, p<0.01) or overactive bladder symptoms (OR 1.9, 95% CI 1.1-15.2, p<0.01).
These data suggest that there is a link between NE in childhood and nocturia in adulthood. A strong relationship was found between overactive bladder in children and overactive bladder in their mothers.
本研究旨在探讨儿童夜间遗尿（NE）与父母夜尿症之间的关系。
该研究在意大利那不勒斯ASL NA 1的普通儿科医生网络中进行。所有患有NE的儿童及其母亲均被邀请到诊所参与研究。通过个人访谈收集数据。所有儿童均记录了一份为期5天的膀胱日记。有夜尿症的母亲需填写一份为期3天的排尿频率 - 尿量图表，以评估夜间多尿或膀胱容量减少的情况。儿童和母亲均接受膀胱超声扫描以测量膀胱壁厚度。
共调查了224名母亲（年龄在23至45岁之间，平均33.3±4.1岁）及其225名儿童（年龄在7至13岁之间，平均8.35±1.81岁）。在224名母亲中，90名（40%）有夜尿症，其中55名（61%）清楚记得自己童年时曾患过NE。在35名无夜尿症的女性中，只有4名（11%）有NE（p<0.001）。NE持续到11岁以上的儿童更有可能有患夜尿症的父母。非单纯症状性NE的儿童更有可能有患夜尿症的母亲（优势比（OR）1.7，95%置信区间（CI）1.2 - 7.1，p<0.01）或膀胱过度活动症症状（OR 1.9，95% CI 1.1 - 15.2，p<0.01）。
这些数据表明儿童期NE与成年期夜尿症之间存在联系。发现儿童膀胱过度活动症与其母亲的膀胱过度活动症之间存在密切关系。
