Warren Alpert Medical School of Brown University, the Department of Pathology and Laboratory Medicine, Lifespan Academic Medical Center, and the Department of Medicine, Women and Infants Hospital, Providence, Rhode Island.
Obstet Gynecol. 2020 Feb;135(2):383-386. doi: 10.1097/AOG.0000000000003654.
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin's lymphoma affecting pregnancy. These tumors may be aggressive and rapidly growing in pregnancy. Management is based on the balance of risks and benefits to both the pregnant patient and the fetus.
We present a case of diffuse large B-cell lymphoma diagnosed in the third trimester of pregnancy. The patient underwent labor induction at 34 weeks of gestation, started a standard chemotherapy protocol postpartum, and breastfed following a timed lactation protocol.
Management of lymphoma during pregnancy highlights the need to consider all aspects of proposed oncologic and obstetric care as well as neonatal risks. Considerations highlighted in this case include staging methods, administration of antenatal steroids, timing of delivery, and lactation during chemotherapy.
弥漫性大 B 细胞淋巴瘤是影响妊娠的最常见的非霍奇金淋巴瘤。这些肿瘤在妊娠期间可能具有侵袭性且生长迅速。治疗管理基于对孕妇和胎儿的风险和获益进行权衡。
我们报告了一例在妊娠晚期诊断出的弥漫性大 B 细胞淋巴瘤病例。该患者在妊娠 34 周时进行了引产，在产后开始了标准的化疗方案，并按照定时哺乳方案进行了母乳喂养。
妊娠期间淋巴瘤的管理强调需要考虑提出的肿瘤学和产科护理以及新生儿风险的各个方面。本病例中强调的考虑因素包括分期方法、产前类固醇的使用、分娩时机以及化疗期间的哺乳。
