Department of Experimental Psychology, Institute of Psychology, University of São Paulo, São Paulo, Brazil.
Department of Experimental Psychology, Institute of Psychology, University of São Paulo, São Paulo, Brazil.
J AAPOS. 2020 Feb;24(1):23.e1-23.e6. doi: 10.1016/j.jaapos.2019.11.005. Epub 2020 Jan 8.
To follow the visual acuity development of children exposed to or infected with the Zika virus (ZIKV) during gestation and to relate potential visual acuity deficits to their clinical condition.
In this prospective study, visual acuity was measured via Teller Acuity Cards in three groups of children: (1) those with confirmed ZIKV exposure (ZE) through the mother only, (2) those with confirmed infection (ZI), and (3) unaffected controls. Visual acuity was measured 2-4 times in each child during the first 30 months of age.
The study included 22 children in the ZE group, 11 in the ZI group, and 27 controls. Visual acuity developed normally in both patient groups, including infected patients (ZI) that did not manifest clinical symptoms. In a small subgroup of patients with characteristics consistent with congenital Zika syndrome (CZS), visual acuity was within normative values, with the exception of single child with chorioretinal atrophy.
In this southeastern Brazil study cohort, visual acuity development seemed to progress normally in infected children without CZS symptoms.
观察妊娠期感染或接触寨卡病毒（ZIKV）的儿童的视力发育情况，并将潜在的视力缺陷与其临床状况联系起来。
本前瞻性研究通过 Teller 视力卡对三组儿童的视力进行了测量：（1）仅通过母亲确认 ZIKV 暴露（ZE）的儿童，（2）确诊感染（ZI）的儿童，和（3）未受影响的对照组儿童。在儿童生命的前 30 个月中，对每个儿童进行了 2-4 次视力测量。
该研究包括 ZE 组的 22 名儿童、ZI 组的 11 名儿童和 27 名对照组儿童。两个患者组的视力发育正常，包括没有表现出临床症状的感染患者（ZI）。在一小部分具有先天性寨卡综合征（CZS）特征的患者中，除了一名患有脉络膜视网膜萎缩的儿童外，视力均处于正常值范围内。
在巴西东南部的本研究队列中，没有 CZS 症状的感染儿童的视力发育似乎正常。
