Baran Luiz C P, Lima Diego da S, Silva Leonardo A, Tabares Heydi S, Dias Sarah L, Zin Andrea Araújo, Moreira Maria E L, da Costa Marcelo F, Ventura Dora F
Department of Experimental Psychology, Institute of Psychology, University of São Paulo, São Paulo, SP, Brazil.
Nucleus of Neurosciences and Behavior, University of São Paulo, São Paulo, SP, Brazil.
Front Ophthalmol (Lausanne). 2022 Nov 29;2:948409. doi: 10.3389/fopht.2022.948409. eCollection 2022.
This study aimed to assess visual acuity (VA) in Congenital Zika Syndrome (CZS)-children to evaluate visual loss. To that end we evaluated 41 CZS - children, from Rio de Janeiro using Teller Acuity Cards.
To asses VA, we evaluated 41 CZS - children, from Rio de Janeiro using Teller Acuity Cards. The children had Zika virus-infection confirmed by reverse transcription-polymerase chain reaction (RT-PCR) or clinical evaluation.
In 39 out of 41 (95%) children, the VA scores were below normative values, while in 10 cases, VA was only marginally below normal; in the remaining 29 cases, VA was more than 0.15 logMAR below the lower limit. There was no correlation between VA and the cognitive domain tasks, although there was a correlation between VA and motor domain tasks. Thirty-seven children performed at least one task in the cognitive set, while fourteen children did not perform any task in the motor set. Children with VA above the lower limit performed better in the cognitive and motor tasks.
We concluded that ZIKV- infected children with CZS were highly VA impaired which correlated with motor performance, but not with cognitive performance. Part of the children had VA within the normal limits and displayed better performance in the cognitive and motor sets. Therefore, even if heavily impaired, most children had some degree of VA and visual function.
本研究旨在评估先天性寨卡综合征（CZS）患儿的视力（VA），以评估视力丧失情况。为此，我们使用泰勒视力卡片对来自里约热内卢的41名CZS患儿进行了评估。
为评估视力，我们使用泰勒视力卡片对来自里约热内卢的41名CZS患儿进行了评估。这些患儿通过逆转录聚合酶链反应（RT-PCR）或临床评估确诊感染寨卡病毒。
41名患儿中有39名（95%）的视力得分低于正常标准值，其中10例视力仅略低于正常；在其余29例中，视力比下限低超过0.15对数最小分辨角（logMAR）。视力与认知领域任务之间无相关性，尽管视力与运动领域任务之间存在相关性。37名儿童在认知组中至少完成了一项任务，而14名儿童在运动组中未完成任何任务。视力高于下限的儿童在认知和运动任务中表现更好。
我们得出结论，感染寨卡病毒的CZS患儿视力严重受损，这与运动表现相关，但与认知表现无关。部分患儿视力在正常范围内，在认知和运动组中表现更好。因此，即使严重受损，大多数患儿仍有一定程度的视力和视觉功能。
