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193纳米准分子激光对豚鼠活体表皮的选择性消融

193 nm excimer laser selective ablation of in vivo guinea pig epidermis.

作者信息

Morelli J G, Kibbi A G, Boll J, Tan O T

机构信息

Department of Dermatology, University of Colorado Medical Center, Denver.

出版信息

J Invest Dermatol. 1988 Dec;91(6):532-5. doi: 10.1111/1523-1747.ep12476881.

DOI:10.1111/1523-1747.ep12476881
PMID:3192952
Abstract

We have previously shown that 193 nm excimer laser irradiation cleanly and effectively ablates avascular tissue with minimal thermal damage to surrounding adjacent structures. In this study, the 193 nm excimer laser is used to remove guinea pig epidermis in vivo. The epidermis can be totally ablated with thermal damage extending only superficially into the dermis. Reepitheliazation of the ablated area takes place in 1 week or less. This technique may be applicable to the removal of benign epidermal lesions.

摘要

我们之前已经表明,193纳米准分子激光照射能够干净、有效地消融无血管组织,对周围相邻结构的热损伤极小。在本研究中,193纳米准分子激光用于在体内去除豚鼠表皮。表皮能够被完全消融,热损伤仅浅表地延伸至真皮。消融区域在1周或更短时间内实现上皮再形成。该技术可能适用于去除良性表皮病变。

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