Zhao Weigang, Chen Tangbing, Yang Yi
Department of Thoracic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200030, China.
Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
Ann Transl Med. 2019 Nov;7(22):703. doi: 10.21037/atm.2019.09.42.
Primary extragenital choriocarcinoma is a highly malignant tumor and usually occurs in the midline of the body, such as the mediastinum, retroperitoneum, pineal gland and the middle part of the brain. In this report we present a case of primary extragenital choriocarcinoma located in the posterior mediastinum. A 40-year-old man was admitted to hospital with severe chest wall pain for 2 months. Enhanced chest computed tomography (CT) showed a mass of soft tissue measuring 5.2 cm × 4.5 cm located in the posterior mediastinum. CT-guided percutaneous fine needle aspiration (FNA) biopsy was performed and adenocarcinoma was diagnosed. After careful examination, complete tumor resection with combined resection of part left upper lobe of lung and lymph node dissection were performed. Combining hematoxylin/eosin staining and immunohistochemical a pathological diagnosis of choriocarcinoma was made.
原发性生殖器外绒毛膜癌是一种高度恶性的肿瘤，通常发生在身体中线部位，如纵隔、腹膜后、松果体和脑中部。在本报告中，我们呈现了一例位于后纵隔的原发性生殖器外绒毛膜癌病例。一名40岁男性因严重胸壁疼痛2个月入院。胸部增强计算机断层扫描（CT）显示后纵隔有一个5.2厘米×4.5厘米的软组织肿块。进行了CT引导下经皮细针穿刺抽吸（FNA）活检，诊断为腺癌。经过仔细检查，进行了肿瘤完整切除，同时联合切除部分左肺上叶并进行淋巴结清扫。结合苏木精/伊红染色和免疫组化做出了绒毛膜癌的病理诊断。
