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使用生命历程图表评估和比较不同使用者群体中苯丙胺类兴奋剂使用轨迹:一项横断面研究。

Using life course charts to assess and compare trajectories of amphetamine type stimulant consumption in different user groups: a cross-sectional study.

机构信息

Department of Addictology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.

Centre of Interdisciplinary Addiction Research of Hamburg University (ZIS), Department of Psychiatry, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Harm Reduct J. 2020 Jan 13;17(1):8. doi: 10.1186/s12954-019-0339-x.

Abstract

BACKGROUND

Amphetamine-type stimulants (ATS) are the second most commonly used illicit drugs in Europe and globally. However, there is limited understanding of what shapes patterns of ATS use over the life course. The ATTUNE project "Understanding Pathways to Stimulant Use: a mixed methods examination of the individual, social and cultural factors shaping illicit stimulant use across Europe" aims to fill this gap. Here we report initial findings from the life course chart exercise conducted as part of qualitative interviews with ATS users and nonusers.

METHODS

Two hundred seventy-nine in-depth qualitative interviews were conducted with five ATS user groups (current and former dependent users;current and former frequent users;non-frequent users) and one group of exposed non-ATS users in five European countries (Germany, UK, Poland, Netherlands and Czech Republic). As part of the interviews, we used life course charts to capture key life events and substance use histories. Life events were categorised as either positive, neutral or negative, and associated data were analysed systematically to identify differences between user groups. We applied statistical analysis of variance (ANOVA) and analysis of covariance (ANCOVA) to test for group differences.

RESULTS

Out of 3547 life events documented, 1523 life events were categorised as neutral, 1005 life events as positive and 1019 life events as negative. Current and formerly dependent ATS users showed more negative life events for the entire life course after age adjustment. Although some group differences could be attributed to the individuals' life course prior to first ATS use, most negative life events were associated with periods of ATS usage. A detailed analysis of the specific life domains reveals that dominantly, the social environment was affected by negative life events.

CONCLUSIONS

For non-dependent, frequent and non-frequent ATS users, negative life events from the period of ATS use do not become obvious in our analysed data. Besides preventing a pathway into ATS dependency, the aim of an intervention should be to reduce the harm by for example drug testing which offers also the opportunity for interventions to prevent developing a substance use dependency. For the group of dependent ATS users, our study suggests holistic, tailored interventions and specialist treatment services are needed, as a single, simple intervention is unlikely to cover all the life domains affected.

摘要

背景

安非他命类兴奋剂(ATS)是欧洲和全球范围内第二大常用非法药物。然而,对于什么塑造了一生中 ATS 使用模式,人们的理解有限。ATTUNE 项目“了解兴奋剂使用途径:对塑造欧洲各地非法兴奋剂使用的个体、社会和文化因素的混合方法研究”旨在填补这一空白。在这里,我们报告了作为对 ATS 用户和非用户进行定性访谈的一部分进行的生命历程图表练习的初步结果。

方法

在五个欧洲国家(德国、英国、波兰、荷兰和捷克共和国)对五个 ATS 用户群体(当前和以前的依赖使用者;当前和以前的频繁使用者;非频繁使用者)和一个暴露于非 ATS 用户群体进行了 279 次深入的定性访谈。作为访谈的一部分,我们使用生命历程图表来记录关键的生活事件和物质使用史。生活事件分为积极、中性或消极,并对相关数据进行系统分析,以确定用户群体之间的差异。我们应用方差分析(ANOVA)和协方差分析(ANCOVA)来检验组间差异。

结果

在记录的 3547 个生活事件中,有 1523 个生活事件被归类为中性,1005 个生活事件为积极,1019 个生活事件为消极。调整年龄后,当前和以前依赖 ATS 的使用者在整个生命历程中显示出更多的负面生活事件。尽管一些群体差异可以归因于个体在首次使用 ATS 之前的生命历程,但大多数负面生活事件都与 ATS 使用期间有关。对特定生命领域的详细分析表明,主要是社会环境受到负面生活事件的影响。

结论

对于非依赖、频繁和非频繁的 ATS 用户,在我们分析的数据中,ATS 使用期间的负面生活事件并不明显。除了防止进入 ATS 依赖的途径外,干预的目的还应该是通过例如药物测试来减少伤害,这也为干预措施提供了机会,以防止形成物质使用依赖。对于依赖 ATS 的使用者群体,我们的研究表明需要提供全面、量身定制的干预措施和专业治疗服务,因为单一、简单的干预措施不太可能涵盖所有受影响的生活领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffff/6956476/7798c0af7898/12954_2019_339_Fig1_HTML.jpg

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