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Is cinnarizine/betahistine combination superior to respective monotherapies in treatment of vertigo? Comment on a randomized triple-blind placebo-controlled trial.

作者信息

Amini Kiumarth, Taghizadeh-Ghehi Maryam

机构信息

Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, 4th floor, No 92, Karimkhan Zand Ave., Hafte Tir Sq, Tehran, Iran.

出版信息

Eur J Clin Pharmacol. 2020 Apr;76(4):607-608. doi: 10.1007/s00228-020-02833-z. Epub 2020 Jan 14.

DOI:10.1007/s00228-020-02833-z
PMID:31932873
Abstract
摘要

相似文献

1
Is cinnarizine/betahistine combination superior to respective monotherapies in treatment of vertigo? Comment on a randomized triple-blind placebo-controlled trial.桂利嗪/倍他司汀联合用药在眩晕治疗中是否优于各自的单一疗法？对一项随机三盲安慰剂对照试验的评论
Eur J Clin Pharmacol. 2020 Apr;76(4):607-608. doi: 10.1007/s00228-020-02833-z. Epub 2020 Jan 14.
2
Comment on "Is cinnarizine/betahistine combination superior to respective monotherapies in treatment of vertigo? A randomized triple-blind placebo-controlled trial".关于《桂利嗪/倍他司汀联合用药在眩晕治疗中是否优于各自的单一疗法？一项随机三盲安慰剂对照试验》的评论
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3
Cinnarizine/betahistine combination vs. the respective monotherapies in acute peripheral vertigo: a randomized triple-blind placebo-controlled trial.桂利嗪/倍他司汀联合治疗与各自单药治疗急性外周性眩晕的随机三盲安慰剂对照试验。
Eur J Clin Pharmacol. 2019 Nov;75(11):1513-1519. doi: 10.1007/s00228-019-02741-x. Epub 2019 Aug 16.
4
Efficacy and Safety of a Fixed Combination of Cinnarizine 20 mg and Dimenhydrinate 40 mg vs Betahistine Dihydrochloride 16 mg in Patients with Peripheral Vestibular Vertigo: A Prospective, Multinational, Multicenter, Double-Blind, Randomized, Non-inferiority Clinical Trial.西尼必利嗪 20 毫克和茶苯海明 40 毫克固定组合与双氢盐酸倍他司汀 16 毫克治疗外周性前庭眩晕患者的疗效和安全性：一项前瞻性、多国、多中心、双盲、随机、非劣效性临床试验。
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Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: a randomized, double-blind, non-inferiority study.比较桂利嗪和茶苯海明固定低剂量联合与倍他司汀治疗前庭神经炎的疗效：一项随机、双盲、非劣效性研究。
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Treatment of vertebrobasilar insufficiency--associated vertigo with a fixed combination of cinnarizine and dimenhydrinate.用桂利嗪和茶苯海明固定复方治疗椎基底动脉供血不足相关性眩晕。
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Fixed combination of cinnarizine and dimenhydrinate versus betahistine dimesylate in the treatment of Ménière's disease: a randomized, double-blind, parallel group clinical study.桂利嗪与茶苯海明固定组合对比甲磺酸倍他司汀治疗梅尼埃病：一项随机、双盲、平行组临床研究
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Comparison of cinnarizine/dimenhydrinate fixed combination with the respective monotherapies for vertigo of various origins: a randomized, double-blind, active-controlled, multicentre study.比较桂利嗪/盐酸苯海拉明固定剂量复方与相应单药治疗各种来源眩晕的疗效：一项随机、双盲、阳性对照、多中心研究。
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Betahistine or Cinnarizine for treatment of Meniere's disease.倍他司汀或桂利嗪治疗梅尼埃病。
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本文引用的文献

1
Efficacy and Safety of a Fixed Combination of Cinnarizine 20 mg and Dimenhydrinate 40 mg vs Betahistine Dihydrochloride 16 mg in Patients with Peripheral Vestibular Vertigo: A Prospective, Multinational, Multicenter, Double-Blind, Randomized, Non-inferiority Clinical Trial.西尼必利嗪 20 毫克和茶苯海明 40 毫克固定组合与双氢盐酸倍他司汀 16 毫克治疗外周性前庭眩晕患者的疗效和安全性：一项前瞻性、多国、多中心、双盲、随机、非劣效性临床试验。
Clin Drug Investig. 2019 Nov;39(11):1045-1056. doi: 10.1007/s40261-019-00858-6.
2
Cinnarizine/betahistine combination vs. the respective monotherapies in acute peripheral vertigo: a randomized triple-blind placebo-controlled trial.桂利嗪/倍他司汀联合治疗与各自单药治疗急性外周性眩晕的随机三盲安慰剂对照试验。
Eur J Clin Pharmacol. 2019 Nov;75(11):1513-1519. doi: 10.1007/s00228-019-02741-x. Epub 2019 Aug 16.
3
Efficacy of acetylleucine in vertigo and dizziness: a systematic review of randomised controlled trials.乙酰亮氨酸治疗眩晕和头晕的疗效：一项随机对照试验的系统评价。
Eur J Clin Pharmacol. 2019 May;75(5):603-607. doi: 10.1007/s00228-018-02617-6. Epub 2019 Jan 6.
4
Betahistine for symptoms of vertigo.倍他司汀用于治疗眩晕症状。
Cochrane Database Syst Rev. 2016 Jun 21;2016(6):CD010696. doi: 10.1002/14651858.CD010696.pub2.
5
Efficacy and Tolerability of a Fixed Combination of Cinnarizine and Dimenhydrinate versus Betahistine in the Treatment of Otogenic Vertigo : A Double-Blind, Randomised Clinical Study.西尼必利嗪和茶苯海明固定组合与倍他司汀治疗耳源性眩晕的疗效和耐受性：一项双盲、随机临床试验。
Clin Drug Investig. 2005;25(6):377-89. doi: 10.2165/00044011-200525060-00003.