Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland, USA
mSphere. 2020 Jan 15;5(1):e00964-19. doi: 10.1128/mSphere.00964-19.
Diana V. Pastrana works in the field of DNA tumor virus biology. In this mSphere of Influence article, she reflects on how the two papers "Donor origin of BKV replication after kidney transplantation" (C. Schmitt, L. Raggub, S. Linnenweber-Held, O. Adams, et al., J Clin Virol 59:120-125, 2014, https://doi.org/10.1016/j.jcv.2013.11.009) and "Neutralizing antibody-mediated response and risk of BK virus-associated nephropathy" (M. Solis, A. Velay, R. Porcher, P. Domingo-Calap, et al., J Am Soc Nephrol 29:326-334, 2018, https://doi.org/10.1681/ASN.2017050532) reminded her of the importance of allowing data, and not adherence to dogma, to drive her research.
戴安娜·帕斯崔纳(Diana V. Pastrana)从事 DNA 肿瘤病毒生物学领域的工作。在本期《mSphere 影响力》文章中,她回顾了两篇论文“肾移植后 BKV 复制的供体起源”(C. Schmitt、L. Raggub、S. Linnenweber-Held、O. Adams 等人,《临床病毒学杂志》59:120-125, 2014, https://doi.org/10.1016/j.jcv.2013.11.009)和“中和抗体介导的反应与 BK 病毒相关性肾病的风险”(M. Solis、A. Velay、R. Porcher、P. Domingo-Calap 等人,《美国肾病学会杂志》29:326-334, 2018, https://doi.org/10.1681/ASN.2017050532)如何使她想起让数据、而不是教条来驱动她的研究的重要性。