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[培养的人淋巴细胞γ射线照射期间DNA复制合成及呼吸作用的变化]

[Change in the replicative synthesis of DNA and in respiration during gamma-irradiation of cultured human lymphocytes].

作者信息

Seĭlanov A S, Kondrashova T V, Konev V V

出版信息

Radiobiologiia. 1988 Sep-Oct;28(5):607-10.

PMID:3194490
Abstract

The onset of 3H-thymidine incorporation in DNA precedes a short-term activation of cell respiration. gamma-Irradiation (5 Gy, 0.1 Gy/s) significantly inhibits oxygen consumption by human peripheral blood lymphocytes. It should be noted that time dependence maxima of oxygen consumption are shifted towards later times of cultivation.

摘要

DNA中3H-胸腺嘧啶核苷掺入的开始先于细胞呼吸的短期激活。γ射线照射（5 Gy，0.1 Gy/s）显著抑制人外周血淋巴细胞的氧消耗。应当指出，氧消耗的时间依赖性最大值向培养后期转移。

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