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胆囊切除术致大胆管损伤的微创治疗。

Minimally invasive surgery for the management of major bile duct injury due to cholecystectomy.

机构信息

Division of General Surgery, Ospedali Riuniti Marche Nord, Pesaro, Italy.

出版信息

J Hepatobiliary Pancreat Sci. 2020 Apr;27(4):157-163. doi: 10.1002/jhbp.710. Epub 2020 Feb 14.

DOI:10.1002/jhbp.710
PMID:31945263
Abstract

BACKGROUND

In recent years there has been a growing interest in the application of minimally invasive surgery in the management of cholecystectomy-related injury to the biliary tract. The aim of this analysis was to identify and combine the available evidence on the argument, with particular reference to major injuries to the main bile duct requiring biliodigestive anastomosis.

METHODS

The PubMed/MEDLINE, Embase, and Web of Science electronic databases were queried through May 2019. Inclusion criteria considered all studies reporting detailed data about patients with bile duct injury following cholecystectomy receiving minimally invasive (both laparoscopic and robotic) surgical repair. Clinical outcomes data were pooled and analyzed.

RESULTS

A total of 31 studies reporting on the outcomes of 218 patients were eventually included in the analysis, whereby 148 patients with type D or E injury. Of these, there were 31 patients (21%) receiving direct bile duct repair and 117 patients (79%) undergoing bilioenteric reconstruction. Among patients with major bile duct injury, postoperative morbidity was 24%, being 12% the incidence of major complications and 6% the rate of patients requiring subsequent, further surgery.

CONCLUSIONS

The absence of high-level evidences precludes the possibility to draw definitive conclusions. However, the available data derived from a growing number of centers demonstrate that minimally invasive surgery may offer its well-known advantages on postoperative outcomes also in the setting of severe iatrogenic injury to the bile ducts.

摘要

背景

近年来,微创外科在处理胆囊切除术后胆道损伤方面的应用引起了越来越多的关注。本分析旨在确定并结合有关主要胆管损伤需要胆肠吻合术的现有证据。

方法

通过 2019 年 5 月,检索了 PubMed/MEDLINE、Embase 和 Web of Science 电子数据库。纳入标准考虑了所有报告胆囊切除术后胆管损伤患者接受微创(腹腔镜和机器人)手术修复详细数据的研究。汇总并分析临床结局数据。

结果

最终纳入了 31 项研究,共报告了 218 例患者的结果,其中 D 型或 E 型损伤患者 148 例。其中,有 31 例(21%)患者接受直接胆管修复,117 例(79%)患者接受胆肠重建。在主要胆管损伤患者中,术后并发症发生率为 24%,其中主要并发症发生率为 12%,需要进一步手术的患者发生率为 6%。

结论

由于缺乏高级别的证据,因此无法得出明确的结论。然而,越来越多的中心提供的数据表明,微创外科在严重医源性胆管损伤的情况下,也可能在术后结果方面具有其众所周知的优势。

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