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重复经颅磁刺激(rTMS)对脑瘫儿童的动态平衡有治疗作用吗?

Does repetitive Transcranial Magnetic Stimulation (rTMS) have therapeutic effects on Dynamic Balance of Children with Cerebral Palsy?

作者信息

Dadashi F, Lotfian M, Rafieenazari Z, Shahroki A, Irani A, Mirbagheri A, Mirbagheri M M

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:425-428. doi: 10.1109/EMBC.2019.8857947.

Abstract

Our big goal in this research was to evaluate the therapeutic effects of repetitive Transcranial Magnetic Stimulation (rTMS) on cerebral palsy (CP) children with balance deficits. Four spastic hemiplegic CP children were participated; the experimental group received rTMS training 4 days a week for 3 weeks and then for the next 3 weeks they received typical occupational therapy just after rTMS therapy. The control group received placebo rTMS instead of real one accordingly. Their dynamic balance was evaluated before the start of the treatment and 6 weeks after it. Center of pressure (COP) and center of mass (COM) features were regarded as dynamic balance parameters. Our results showed that the peak to peak of COP, COM, COM-COP, COM-COP inclination angles all improved for both experimental (15-86%) and control group patients, though there was less improvement about 8-46% in features of the control patients. Our results demonstrate that intensive sessions of the rTMS training could have the potential to enhance the therapeutic effects of typical occupational therapy that can produce dynamic balance improvements in CP children compared to using the occupational therapy by itself.

摘要

我们这项研究的主要目标是评估重复经颅磁刺激(rTMS)对患有平衡缺陷的脑瘫(CP)儿童的治疗效果。四名痉挛性偏瘫型脑瘫儿童参与了研究;实验组每周接受4天的rTMS训练,为期3周,然后在接下来的3周里,他们在rTMS治疗后紧接着接受常规职业治疗。相应地,对照组接受的是安慰剂rTMS而非真正的rTMS。在治疗开始前以及治疗6周后对他们的动态平衡进行了评估。压力中心(COP)和质心(COM)特征被视为动态平衡参数。我们的结果显示,实验组(改善幅度为15 - 86%)和对照组患者的COP峰峰值、COM、COM - COP、COM - COP倾斜角度均有所改善,不过对照组患者各项特征的改善幅度较小,约为8 - 46%。我们的结果表明,与单纯使用职业治疗相比,强化的rTMS训练疗程有可能增强常规职业治疗的治疗效果,而常规职业治疗能够改善脑瘫儿童的动态平衡。

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