用于皮层内微刺激的高密度纳米线电极

High density nanowire electrodes for intracortical microstimulation.

作者信息

Puttaswamy Srinivasu Valagerahally, Shi Qiongfeng, Steele David, Fishlock Sam Jeffery, Lee Chengkuo, McLaughlin James

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:5657-5660. doi: 10.1109/EMBC.2019.8857305.

DOI:10.1109/EMBC.2019.8857305

PMID:31947136

Abstract

High-density electrodes with the nano feature size greatly enhance resolution and specificity during intracortical microstimulation. In this viewpoint, we fabricated and developed high-density nanowire (NW) electrodes, ~ 2.45×10 / cm that could directly stimulate specific region of the cortex with low current amplitude in the range of 120-180 μA. The proposed nanowire electrodes will help expand the capabilities of microstimulation and extend the range of dysfunctions that can be treated using microstimulation technique.

摘要

具有纳米特征尺寸的高密度电极在皮层内微刺激过程中极大地提高了分辨率和特异性。从这个角度来看，我们制造并开发了高密度纳米线（NW）电极，密度约为2.45×10⁶/cm²，能够在120 - 180μA的低电流幅度下直接刺激皮层的特定区域。所提出的纳米线电极将有助于扩展微刺激的能力，并扩大可使用微刺激技术治疗的功能障碍范围。