Ronner S F, Foote W E, Pollen D A
Electroencephalogr Clin Neurophysiol. 1981 Oct;52(4):375-7. doi: 10.1016/0013-4694(81)90067-5.
The response of visual cortex neurons to local intracortical microstimulation was measured in the anesthetized cat. When the recording microelectrode was very close (about 20 micrometers) to the tip of the stimulating electrode, threshold currents as low as 10 micro A were capable of firing neurons. Over a 20-fold range in distance from the site of stimulation, an 80-fold increase in threshold current was observed. The mean latency of activation for 30 neurons tested with intracortical stimulation was 2.88 +/- 0.45 msec. The majority of these cells were probably synaptically activated. The mean threshold current for these neurons was 0.55 +/- 0.12 mA (N = 30). These values were significantly smaller than the thresholds found previously when stimulating electrodes were located on the pia-arachnoid surface of the visual cortex.
在麻醉猫身上测量了视觉皮层神经元对局部皮层内微刺激的反应。当记录微电极非常靠近（约20微米）刺激电极尖端时，低至10微安的阈值电流就能激发神经元。在距刺激部位20倍的距离范围内，观察到阈值电流增加了80倍。用皮层内刺激测试的30个神经元的平均激活潜伏期为2.88±0.45毫秒。这些细胞中的大多数可能是通过突触激活的。这些神经元的平均阈值电流为0.55±0.12毫安（N = 30）。这些值明显小于先前将刺激电极置于视觉皮层软脑膜表面时发现的阈值。
