Gonzalez-Barcala Francisco-Javier, Nieto-Fontarigo Juan-José, Lourido-Cebreiro Tamara, Rodríguez-García Carlota, San-Jose Maria-Esther, Carreira Jose-Martín, Calvo-Alvarez Uxio, Cruz Maria-Jesus, Facal David, Garcia-Sanz Maria-Teresa, Valdes-Cuadrado Luis, Salgado Francisco-Javier
Department of Medicine, Universidade de Santiago de Compostela, 15705 Santiago de Compostela, Spain.
Spanish Biomedical Research Networking Centre-CIBERES, 28029 Madrid, Spain.
J Clin Med. 2020 Jan 14;9(1):221. doi: 10.3390/jcm9010221.
The relationship between obesity and asthma exacerbations is still under debate. The aim of our work is to analyse the relationship between obesity and hospital re-admissions in asthmatics. A review was retrospectively performed on all hospital admissions of adult patients due to asthma exacerbation occurring in our hospital for 11 years. All those cases with asthma as the first diagnosis in the discharge report were included, or those with asthma as the second diagnosis provided when the first diagnosis was respiratory infection or respiratory failure. Only the first hospital admission of each patient was included in this study. The Odds Ratios of a higher incidence of early/late readmissions due to asthma exacerbation were calculated using a binary logistic regression, using the body mass index (BMI) as independent variable, adjusted for all the variables included in the study. The study included 809 patients with a mean age of 55.6 years, and 65.2% were female. The majority (71.4%) were obese or overweight. No significant relationship was observed in the univariate or multivariate analyses between overweight or obesity and the early or late hospital readmissions due to asthma. Therefore, obesity does not seem to be a determining factor in the risk of asthma exacerbations.
肥胖与哮喘急性发作之间的关系仍存在争议。我们这项工作的目的是分析肥胖与哮喘患者再次入院之间的关系。我们对我院11年间因哮喘急性发作而住院的所有成年患者进行了回顾性研究。纳入出院报告中以哮喘作为第一诊断的所有病例，或者第一诊断为呼吸道感染或呼吸衰竭时以哮喘作为第二诊断的病例。本研究仅纳入每位患者的首次住院情况。以体重指数（BMI）作为自变量，对研究中包含的所有变量进行校正，采用二元逻辑回归计算因哮喘急性发作导致早期/晚期再次入院发生率较高的比值比。该研究纳入了809例患者，平均年龄为55.6岁，65.2%为女性。大多数（71.4%）为肥胖或超重。在单因素或多因素分析中，未观察到超重或肥胖与因哮喘导致的早期或晚期再次入院之间存在显著关系。因此，肥胖似乎不是哮喘急性发作风险的决定性因素。
