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红皮病作为肺鳞状细胞癌的首发表现:罕见病例报告

Erythroderma as first manifestation of squamous cell lung cancer: rare case report.

作者信息

Arandes-Marcocci Jorge, Iglesias-Sancho Maribel, Setó-Torrent Núria, Fernández-Figueras María Teresa

机构信息

Hospital Universitari Sagrat Cor-Grupo Quirónsalud, Barcelona, Spain.

Hospital Universitari Sagrat Cor-Grupo Quirónsalud, Barcelona, Spain.

出版信息

An Bras Dermatol. 2020 Jan-Feb;95(1):67-70. doi: 10.1016/j.abd.2019.05.004. Epub 2019 Dec 31.

DOI:10.1016/j.abd.2019.05.004
PMID:31952995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7058868/
Abstract

Erythroderma as the first manifestation of a solid organ malignancy is rare. The underlying cancer is a challenging condition to diagnose. There are a few cases of erythroderma in cancer patients reported in the literature. We here describe the case of a 70-year-old man who presented with asthenia, weight loss, dry cough and total body erythema with desquamation over the past month. A chest computed tomography scan showed a nodular lesion, which was finally diagnosed as a squamous cell lung carcinoma. To our knowledge, as an erythroderma presentation, only 13 cases have been reported in the literature. This case report demonstrates the need to search for a neoplasm in patients presenting with erythroderma, particularly in the presence of accompanying debilitating symptoms.

摘要

红皮病作为实体器官恶性肿瘤的首发表现较为罕见。潜在的癌症诊断颇具挑战性。文献中报道了一些癌症患者出现红皮病的病例。我们在此描述一例70岁男性患者,该患者在过去一个月出现乏力、体重减轻、干咳及全身红斑伴脱屑。胸部计算机断层扫描显示有一个结节性病变,最终被诊断为肺鳞状细胞癌。据我们所知,作为红皮病表现,文献中仅报道了13例。本病例报告表明,对于出现红皮病的患者,尤其是伴有衰弱症状时,有必要排查肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/601f7e66d074/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/9a85d7de6133/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/a402f91a11a0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/ec556e104729/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/378afe2665c9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/601f7e66d074/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/9a85d7de6133/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/a402f91a11a0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/ec556e104729/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/378afe2665c9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3e/7058868/601f7e66d074/gr5.jpg

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本文引用的文献

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A review of the diagnosis and management of erythroderma (generalized red skin).红皮病(全身性皮肤发红)的诊断与管理综述
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Int J Dermatol. 2004 Jan;43(1):39-47. doi: 10.1111/j.1365-4632.2004.01975.x.