BACKGROUND: Spinal cord injury (SCI) could cause motor, sensory loss, severe functional insufficiency, and social problems. This study aims to provide a holistic summary of the global scientific outputs about SCI through bibliometric analyses and reveal the trend topics. METHODS: All publications about SCI published between 1980 and 2018 in Web of Science (WoS) index were downloaded (Access date: 01.09.2019) and analyzed using bibliometric methods. In the Title search section in WoS, the documents with the words "spinal cord injury" were identified. Correlation analysis between SCI publication productivity and economic development indicators of the world countries were analyzed using the Spearman correlation coefficient. RESULTS: There were 20,322 publications, 13,662 of which were articles. The top 3 productive countries were the USA, China, and Canada. British Columbia (403; 2.9%), Toronto (401; 2.9%), and Miami (387; 2.8%) were the prominent cities. The top productive journals were Spinal Cord (1,399; 10.24%), Archives of Physical Medicine and Rehabilitation (835; 6.11%), and Journal of Neurotrauma (631; 4.61%). A statistically significant, high-level correlation was found between the number of publications about SCI and the countries' gross domestic product and gross domestic product per capita (r = 0.711, P < 0.001; r = 0.699, P < 0.001). CONCLUSIONS: This study provides a systematic analysis of SCI and could be a beneficial guide for clinicians and scientists.